Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PFKFB3 | Q16875 | 8/20 | 0.34 |
| ▸ | PFKFB4 | Q16877 | 4/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | SCN4A | P35499 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25465435 | 0.82 | CYP2A6 (0.33) | — | |
| SCHEMBL24947779 | 0.76 | PIM3 (0.39) | PIM1PIM2 | |
| SCHEMBL19266766 | 0.75 | GPR3 (0.39) | RAB9ASMN1; SMN2LMNA | |
| SCHEMBL20842845 | 0.74 | MAPT (0.33) | SMN1; SMN2 | |
| SCHEMBL20114351 | 0.73 | PFKFB3 (0.43) | PFKFB3PFKFB4PIM1PIM2NPC1 | |
| SCHEMBL22432625 | 0.73 | BCL2L1 (0.36) | NPC1RAB9ALMNA | |
| SCHEMBL20079933 | 0.72 | SMN1; SMN2 (0.39) | PFKFB3NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL21755429 | 0.72 | ALOX5 (0.31) | — | |
| SCHEMBL24513138 | 0.70 | LMNA (0.37) | PFKFB3PFKFB4PIM1PIM2NPC1 | |
| SCHEMBL13522721 | 0.70 | NPC1 (0.44) | PFKFB3PFKFB4PIM1PIM2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3312167-A1 | AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME | Idemitsu Kosan Co., Ltd. (JP) | 2018-04-25 | — | — | EP | disclosed |