Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | FDPS | P14324 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL199289 | 0.95 | ALDH1A1 (0.46) | ALDH1A1TDP1CYP3A4TSHRLMNA | |
| SCHEMBL80059 | 0.95 | ALDH1A1 (0.35) | ALDH1A1TDP1CYP3A4TSHRLMNA | |
| SCHEMBL199110 | 0.92 | LMNA (0.46) | ALDH1A1TDP1CYP3A4TSHRLMNA | |
| SCHEMBL200840 | 0.92 | ALDH1A1 (0.41) | ALDH1A1TDP1CYP3A4TSHRLMNA | |
| SCHEMBL25185563 | 0.90 | LMNA (0.44) | ALDH1A1TDP1CYP3A4TSHRLMNA | |
| SCHEMBL200485 | 0.90 | LMNA (0.50) | ALDH1A1TDP1TSHRLMNADNM1 | |
| SCHEMBL25182564 | 0.90 | LMNA (0.44) | ALDH1A1TDP1CYP3A4TSHRLMNA | |
| SCHEMBL198916 | 0.90 | LMNA (0.50) | ALDH1A1TDP1TSHRLMNADNM1 | |
| SCHEMBL25178916 | 0.90 | LMNA (0.44) | ALDH1A1TDP1CYP3A4TSHRLMNA | |
| SCHEMBL199442 | 0.90 | LMNA (0.44) | ALDH1A1TDP1CYP3A4TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 147 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060264669-A1 | preparing a penta-alkyl DTPA (Diethylene Triamine Penta-acetic Acid) to be processed through regioselective hydrolysis with a metal ion as catalyst to obtain a tetra-alkyl DTPA, which is a monoreactive DTPA derivative, to be applied in related industries of imaging agents, medical services and chemistry | ATOMIC ENERGY COUNCIL - INSTITUTE OF NUCLEAR ENERGY RESEARCH | 2006-11-23 | — | — | US | claimed |
| US-5352689-A | Rhizoxin derivatives and their use as anti-tumor agents | SANKYO COMPANY, LIMITED (JP) | 1994-10-04 | — | — | US | claimed |
| CN-118201905-A | Cationic lipid | 武田药品工业株式会社 | 2024-06-14 | — | — | CN | disclosed |
| US-11970610-B2 | Tire rubber composition using pyrazalone-based compound | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2024-04-30 | — | — | US | disclosed |
| US-20240117150-A1 | EXPANSION RATIO IMPROVER FOR POLYMER MATERIALS, FOAMING AGENT COMPOSITION FOR POLYMER MATERIALS, AND RESIN COMPOSITION | OTSUKA CHEMICAL CO., LTD. (JP) | 2024-04-11 | — | — | US | disclosed |
| WO-2024071281-A1 | ASYMMETRIC ALLYL FLUORIDE COMPOUND AND METHOD FOR PRODUCING SAME | シンクレスト株式会社 | 2024-04-04 | — | — | WO | disclosed |
| US-20240059838-A1 | ALKOXYLATED POLYMERIC N-(HYDROXYALKYL)AMINE AS WETTING AGENTS AND AS A COMPONENT OF DEFOAMER COMPOSITIONS | BASF SE (DE) | 2024-02-22 | — | — | US | disclosed |
| US-20240043645-A1 | RUBBER COMPOSITION FOR PRODUCING FOAM HAVING HIGH EXPANSION RATIO, FOAM HAVING HIGH EXPANSION RATIO, TIRE, ACOUSTIC MEMBER, SEALING MATERIAL, HOSE, BELT, WIRE COVERING, THERMAL INSULATION MATERIAL, EXPANSION RATIO IMPROVER FOR RUBBERS, METHOD FOR IMPROVING EXPANSION RATIO OF FOAM, AND METHOD FOR PRODUCING FOAM HAVING HIGH EXPANSION RATIO | OTSUKA CHEMICAL CO., LTD. (JP) | 2024-02-08 | — | — | US | disclosed |
| WO-2023243699-A1 | AMINO ACID HAVING FLUORINE AT α-POSITION, AND DERIVATIVE OF SAME | シンクレスト株式会社 | 2023-12-21 | — | — | WO | disclosed |
| WO-2023243700-A1 | DIFLUOROALDEHYDE, EPOXY, AND DERIVATIVE THEREOF | シンクレスト株式会社 | 2023-12-21 | — | — | WO | disclosed |
| CN-117186510-A | Rubber composition, rubber material, use thereof, and additive | 大塚化学株式会社 | 2023-12-08 | — | — | CN | disclosed |
| EP-0218310-B1 | RHIZOXIN DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL USE | SANKYO COMPANY LIMITED (JP) | 1991-03-13 | — | — | EP | disclosed |
| EP-0395446-A2 | N-acryloylpiperazine derivatives, their preparation and their use as paf antagonists | Sankyo Company Limited (JP) | 1990-10-31 | — | — | EP | disclosed |
| EP-0363223-A2 | 3-Aryloxymethyl-cephalosporin derivatives, their preparation and their medical use | Sankyo Company Limited (JP) | 1990-04-11 | — | — | EP | disclosed |
| EP-0353047-A2 | Use of imidazopyrazole derivatives as analgesics and anti-inflammatory agents | Sankyo Company Limited (JP) | 1990-01-31 | — | — | EP | disclosed |
| EP-0350315-A1 | Rhizoxin derivates and their use as anti-tumor agents | SANKYO COMPANY LIMITED (JP) | 1990-01-10 | — | — | EP | disclosed |
| US-4791128-A | Rhizoxin esters and salts, their pharmaceutical use as anti-tumor agents | SANKYO COMPANY LIMITED (JP) | 1988-12-13 | — | — | US | disclosed |
| EP-0218310-A2 | Rhizoxin derivatives, their preparation and pharmaceutical use | SANKYO COMPANY LIMITED (JP) | 1987-04-15 | — | — | EP | disclosed |
| CN-86102020-A | The preparation method of rhizoxin derivatives and in pharmaceutically application | — | 1986-10-01 | — | — | CN | disclosed |
| US-4473507-A | Controlled release laundry bleach product | THE PROCTER & GAMBLE COMPANY (US) | 1984-09-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060264669-A1 | preparing a penta-alkyl DTPA (Diethylene Triamine Penta-acetic Acid) to be processed through regioselective hydrolysis with a metal ion as catalyst to obtain a tetra-alkyl DTPA, which is a monoreactive DTPA derivative, to be applied in related industries of imaging agents, medical services and chemistry | NAAA, APEH, NAA15 | ALDH1A1 2011/4885TDP1 1976/4885CYP3A4 1253/4885 |
| US-20240043645-A1 | RUBBER COMPOSITION FOR PRODUCING FOAM HAVING HIGH EXPANSION RATIO, FOAM HAVING HIGH EXPANSION RATIO, TIRE, ACOUSTIC MEMBER, SEALING MATERIAL, HOSE, BELT, WIRE COVERING, THERMAL INSULATION MATERIAL, EXPANSION RATIO IMPROVER FOR RUBBERS, METHOD FOR IMPROVING EXPANSION RATIO OF FOAM, AND METHOD FOR PRODUCING FOAM HAVING HIGH EXPANSION RATIO | TIPRL, HEATR1, HNRNPL | ALDH1A1 3059/4885TDP1 2239/4885CYP3A4 4321/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.