Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1B1 | Q16678 | 13/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | BRD1 | O95696 | 1/20 | 0.44 |
| ▸ | TAF1 | P21675 | 1/20 | 0.44 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.44 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4866412 | 0.76 | CYP1B1 (0.69) | CYP1B1LMNAALDH1A1POLBKDM4E | |
| SCHEMBL30905987 | 0.76 | CYP1B1 (0.69) | CYP1B1LMNAALDH1A1POLBKDM4E | |
| SCHEMBL23340159 | 0.73 | CYP11B2 (0.56) | CYP1B1ALDH1A1KDM4EMEN1MAPT | |
| SCHEMBL12561180 | 0.73 | PKM (0.57) | CYP1B1LMNAALDH1A1POLBKDM4E | |
| SCHEMBL30517121 | 0.73 | PKM (0.57) | CYP1B1LMNAALDH1A1POLBKDM4E | |
| SCHEMBL30517035 | 0.72 | ALDH1A1 (0.55) | CYP1B1ALDH1A1POLBKDM4EMEN1 | |
| SCHEMBL3583801 | 0.72 | ALDH1A1 (0.55) | CYP1B1ALDH1A1POLBKDM4EMEN1 | |
| SCHEMBL29822885 | 0.72 | ALDH1A1 (0.55) | CYP1B1ALDH1A1POLBKDM4EMEN1 | |
| SCHEMBL1333882 | 0.72 | PIM1 (0.46) | CYP1B1ALDH1A1POLBMEN1KMT2A | |
| SCHEMBL13727049 | 0.71 | TYMS (0.66) | CYP1B1LMNAALDH1A1POLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1963436-B1 | SPECIFIC DYES OF NAPHTHALIMIDE TYPE, DYEING COMPOSITION COMPRISING AT LEAST ONE SUCH DYE, METHOD OF IMPLEMENTATION AND USES | OREAL (FR) | 2018-04-25 | — | — | EP | disclosed |