SCHEMBL4866412

SCHEMBL4866412

CN1C(=O)c2cccc3c(Br)ccc(c23)C1=O

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1B1 Q16678 11/20 0.69
MEN1 O00255 4/20 0.65
KMT2A Q03164 4/20 0.65
ALDH1A1 P00352 3/20 0.65
USP2 O75604 2/20 0.65
KEAP1 Q14145 2/20 0.65
NFE2L2 Q16236 2/20 0.65
KDM4E B2RXH2 2/20 0.65
ATM Q13315 1/20 0.65
HPGD P15428 1/20 0.65
POLB P06746 3/20 0.61
PRMT1 Q99873 1/20 0.61
LMNA P02545 2/20 0.61
NPC1 O15118 1/20 0.61
MAPT P10636 1/20 0.61
PABPC1 P11940 1/20 0.61
RXFP1 Q9HBX9 1/20 0.59
TP53 P04637 2/20 0.58
L3MBTL1 Q9Y468 2/20 0.58
THRB P10828 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30905987 1.00 CYP1B1 (0.69) CYP1B1MEN1KMT2AALDH1A1USP2
SCHEMBL12869513 0.88 CYP1B1 (0.55) CYP1B1MEN1KMT2AALDH1A1USP2
SCHEMBL30517121 0.86 PKM (0.57) CYP1B1MEN1KMT2AALDH1A1KDM4E
SCHEMBL12561180 0.86 PKM (0.57) CYP1B1MEN1KMT2AALDH1A1KDM4E
SCHEMBL11211857 0.86 CYP1B1 (0.56) CYP1B1MEN1KMT2AALDH1A1USP2
SCHEMBL12869500 0.85 KMT2A (0.73) CYP1B1MEN1KMT2AALDH1A1USP2
SCHEMBL20735127 0.83 KMT2A (0.71) CYP1B1MEN1KMT2AALDH1A1USP2
SCHEMBL20419197 0.82 CYP1B1 (0.78) CYP1B1MEN1KMT2AALDH1A1KDM4E
SCHEMBL29697183 0.82 CYP1B1 (0.78) CYP1B1MEN1KMT2AALDH1A1KDM4E
SCHEMBL7703829 0.82 POLB (0.65) CYP1B1MEN1KMT2AALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112940714-B Wash-free Halo-tag probe with high fluorescence quantum yield and synthetic method and application thereof 中国科学院大连化学物理研究所 2022-11-15 CN claimed
CN-112939936-B Carbonyl azetidine substituted naphthalimide fluorescent dye and synthetic method and application thereof 中国科学院大连化学物理研究所 2022-11-15 CN claimed
CN-112939936-A Carbonyl azetidine substituted naphthalimide fluorescent dye and synthetic method and application thereof 中国科学院大连化学物理研究所 2021-06-11 CN claimed
CN-112940714-A Wash-free Halo-tag probe with high fluorescence quantum yield and synthetic method and application thereof 中国科学院大连化学物理研究所 2021-06-11 CN claimed
US-20240196741-A1 ORGANIC COMPOUND, OPTO-ELECTRONIC DEVICE INCLUDING THE SAME, ELECTRONIC APPARATUS INCLUDING THE OPTO-ELECTRONIC DEVICE, AND ELECTRONIC DEVICE INCLUDING THE ELECTRONIC APPARATUS SAMSUNG DISPLAY CO., LTD. (KR) 2024-06-13 US disclosed
US-20230209862-A1 ORGANIC LIGHT-EMITTING DEVICE AND ELECTRONIC APPARATUS INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-29 US disclosed
US-20230209862-A1 ORGANIC LIGHT-EMITTING DEVICE AND ELECTRONIC APPARATUS INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-29 US disclosed
US-11641754-B2 Organic light-emitting device and electronic apparatus including the same SAMSUNG DISPLAY CO., LTD. (KR) 2023-05-02 US disclosed
US-11641754-B2 Organic light-emitting device and electronic apparatus including the same SAMSUNG DISPLAY CO., LTD. (KR) 2023-05-02 US disclosed
CN-112940714-B Wash-free Halo-tag probe with high fluorescence quantum yield and synthetic method and application thereof 中国科学院大连化学物理研究所 2022-11-15 CN disclosed
CN-112939936-B Carbonyl azetidine substituted naphthalimide fluorescent dye and synthetic method and application thereof 中国科学院大连化学物理研究所 2022-11-15 CN disclosed
CN-114653399-A Organic photocatalyst based on naphthalimide framework 兰州大学 2022-06-24 CN disclosed
US-7988741-B2 Specific naphthalmide-type dyes, dye composition comprising at least one such dye, process using same and uses L'OREAL S.A. (FR) 2011-08-02 US disclosed
US-20110113572-A1 SPECIFIC NAPHTHALMIDE-TYPE DYES, DYE COMPOSITION COMPRISING AT LEAST ONE SUCH DYE, PROCESS USING SAME AND USES L' OREAL S.A. (FR) 2011-05-19 US disclosed
US-20110113572-A1 SPECIFIC NAPHTHALMIDE-TYPE DYES, DYE COMPOSITION COMPRISING AT LEAST ONE SUCH DYE, PROCESS USING SAME AND USES L' OREAL S.A. (FR) 2011-05-19 US disclosed
US-20110042651-A1 LIQUID CRYSTALLINE RYLENE TETRACARBOXYLIC ACID DERIVATIVES AND USE THEREOF BASF SE (DE) 2011-02-24 US disclosed
CN-101974002-A Naphthapyran derivative containing sulfonamide groups UNIV EAST CHINA SCIENCE & TECH 2011-02-16 CN disclosed
US-7358362-B2 Method for the production of terylene-3,4:11,12-tetracarboxydiimides by direct synthesis BASF AKTIENGESELLSCHAFT (DE) 2008-04-15 US disclosed
WO-2007110530-A2 SPECIFIC DYES OF NAPHTHALIMIDE TYPE, DYEING COMPOSITION COMPRISING AT LEAST ONE SUCH DYE, METHOD OF IMPLEMENTATION AND USES L'OREAL (FR) 2007-10-04 WO disclosed
US-20070155968-A1 Method for the production of terylene-3,4:11,12-tetracarboxydiimides by direct synthesis BASF AKTIENGESELLSCHAFT (DE) 2007-07-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110113572-A1 SPECIFIC NAPHTHALMIDE-TYPE DYES, DYE COMPOSITION COMPRISING AT LEAST ONE SUCH DYE, PROCESS USING SAME AND USES KRT18, NEFM, NDC1 CYP1B1 1381/4885MEN1 2652/4885KMT2A 2748/4885
US-20070155968-A1 Method for the production of terylene-3,4:11,12-tetracarboxydiimides by direct synthesis HACL2, HRH3, HCN2 CYP1B1 748/4885MEN1 959/4885KMT2A 717/4885
US-20110042651-A1 LIQUID CRYSTALLINE RYLENE TETRACARBOXYLIC ACID DERIVATIVES AND USE THEREOF TPR, ROR1, CA3 CYP1B1 4192/4885MEN1 1342/4885KMT2A 3067/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.