Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ATF1 | P18846 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2484277 | 0.88 | MAPT (0.53) | ALDH1A1MAPTKMT2AMEN1RAB9A | |
| SCHEMBL18314216 | 0.87 | ALDH1A1 (0.54) | ALDH1A1MAPTKMT2AMEN1RAB9A | |
| SCHEMBL2490668 | 0.86 | RAB9A (0.67) | ALDH1A1MAPTKMT2AMEN1RAB9A | |
| SCHEMBL2417590 | 0.84 | NPC1 (0.65) | ALDH1A1MAPTKMT2AMEN1RAB9A | |
| SCHEMBL16245499 | 0.82 | NPC1 (0.50) | ALDH1A1MAPTKMT2AMEN1RAB9A | |
| SCHEMBL1815768 | 0.76 | MEN1 (0.62) | ALDH1A1MAPTKMT2AMEN1RAB9A | |
| SCHEMBL28350930 | 0.76 | TP53 (0.63) | ALDH1A1MAPTKMT2AMEN1TSHR | |
| SCHEMBL49913 | 0.75 | POLB (0.66) | ALDH1A1KMT2AMEN1TSHRPOLB | |
| SCHEMBL28455181 | 0.73 | MAPT (0.61) | ALDH1A1MAPTKMT2AMEN1RAB9A | |
| Hydrochloric Acid SCHEMBL3584951 | 0.73 | POLB (0.64) | ALDH1A1KMT2AMEN1TSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3312177-A2 | TRICYCLIC DERIVATIVE COMPOUND, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | Jeil Pharmaceutical Co., Ltd. (KR) | 2018-04-25 | — | — | EP | disclosed |