Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 8/20 | 0.62 |
| ▸ | PGR | P06401 | 8/20 | 0.62 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.39 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.39 |
| ▸ | CDK9 | P50750 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2006986 | 0.83 | NR3C1 (0.72) | NR3C1PGRNR3C2CCNT1CDK9 | |
| SCHEMBL2004967 | 0.77 | NR3C1 (0.76) | NR3C1PGRNR3C2CCNT1CDK9 | |
| SCHEMBL2004271 | 0.76 | NR3C1 (0.69) | NR3C1PGRNR3C2CCNT1CDK9 | |
| SCHEMBL2011430 | 0.76 | NR3C1 (0.78) | NR3C1PGRNR3C2CCNT1CDK9 | |
| SCHEMBL2006644 | 0.73 | KDM4E (0.34) | — | |
| SCHEMBL2007148 | 0.66 | LTB4R (0.41) | NR3C1PGRNR3C2 | |
| SCHEMBL4973300 | 0.66 | CYSLTR2 (0.38) | MAPTLMNAMEN1KMT2A | |
| SCHEMBL12161274 | 0.63 | NR3C1 (0.49) | NR3C1PGRMAPTALDH1A1LMNA | |
| SCHEMBL4973294 | 0.63 | ERN1 (0.35) | LMNA | |
| SCHEMBL2007273 | 0.62 | SLC9A1 (0.33) | NR3C1PGRNR3C2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7960365-B2 | Compounds with medicinal effects due to interaction with the glucocorticoid receptor | N.V. ORGANON (NL) | 2011-06-14 | — | — | US | disclosed |