SCHEMBL2008109

SCHEMBL2008109

Cc1cc(C23CC4CC(C2)CC(c2ccc(OCC5CO5)c(C)c2)(C4)C3)ccc1OCC1CO1

nearest known ligand 0.48

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.48
GLA P06280 1/20 0.48
VDR P11473 1/20 0.39
ESR1 P03372 1/20 0.39
TP53 P04637 3/20 0.37
TSHR P16473 3/20 0.37
HIF1A Q16665 3/20 0.37
CYP3A4 P08684 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
KMT2A Q03164 4/20 0.37
MEN1 O00255 3/20 0.37
MAPT P10636 2/20 0.37
HPGD P15428 2/20 0.37
CYP1A2 P05177 1/20 0.37
PPARG P37231 1/20 0.37
PGR P06401 4/20 0.36
TDP1 Q9NUW8 1/20 0.35
GPR55 Q9Y2T6 1/20 0.34
LMNA P02545 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2425547 0.90 ALDH1A1 (0.40) ALDH1A1GLAESR1TP53TSHR
SCHEMBL2004930 0.83 ALDH1A1 (0.38) ALDH1A1GLAESR1TP53TSHR
SCHEMBL2424594 0.82 ALDH1A1 (0.50) ALDH1A1GLAVDRTP53TSHR
SCHEMBL2420659 0.81 KMT2A (0.43) ALDH1A1GLATP53TSHRHIF1A
SCHEMBL3755557 0.81 ALDH1A1 (0.42) ALDH1A1GLAVDRTP53TSHR
SCHEMBL2002765 0.81 SCN9A (0.36) ALDH1A1GLAESR1PGR
SCHEMBL12323206 0.80 ALDH1A1 (0.51) ALDH1A1ESR1TP53TSHRHIF1A
SCHEMBL1673415 0.80 ALDH1A1 (0.51) ALDH1A1ESR1TP53TSHRHIF1A
SCHEMBL549618 0.79 KMT2A (0.41) ALDH1A1GLAVDRTP53TSHR
SCHEMBL6579887 0.79 ALDH1A1 (0.43) ALDH1A1GLAVDRESR1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8017800-B2 Adamantyl group-containing epoxy-modified (meth)acrylate and resin composition containing the same IDEMITSU KOSAN CO., LTD. (JP) 2011-09-13 US claimed
US-20100274043-A1 ADAMANTYL GROUP-CONTAINING EPOXY-MODIFIED (METH)ACRYLATE AND RESIN COMPOSITION CONTAINING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2010-10-28 US claimed
US-8017800-B2 Adamantyl group-containing epoxy-modified (meth)acrylate and resin composition containing the same IDEMITSU KOSAN CO., LTD. (JP) 2011-09-13 US disclosed
US-7960483-B2 Adamantane derivative, composition comprising the derivative, and optical and electronic member using the composition IDEMITSU KOSAN CO., LTD. (JP) 2011-06-14 US disclosed
US-20100274043-A1 ADAMANTYL GROUP-CONTAINING EPOXY-MODIFIED (METH)ACRYLATE AND RESIN COMPOSITION CONTAINING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2010-10-28 US disclosed
US-7790917-B2 Adamantyl group-containing epoxy-modified (meth)acrylate and resin composition containing the same IDEMITSU KOSAN CO., LTD. (JP) 2010-09-07 US disclosed
US-20090099330-A1 ADAMANTYL GROUP-CONTAINING EPOXY-MODIFIED (METH)ACRYLATE AND RESIN COMPOSITION CONTAINING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2009-04-16 US disclosed
US-20090062481-A1 ADAMANTANE DERIVATIVE, COMPOSITION COMPRISING THE DERIVATIVE, AND OPTICAL AND ELECTRONIC MEMBER USING THE COMPOSITION IDEMITSU KOSAN CO., LTD. (JP) 2009-03-05 US disclosed
EP-2014691-A1 ADAMANTYL GROUP-CONTAINING EPOXY-MODIFIED (METH)ACRYLATE AND RESIN COMPOSITION CONTAINING THE SAME Idemitsu Kosan Co., Ltd. (JP) 2009-01-14 EP disclosed
EP-1985617-A1 ADAMANTANE DERIVATIVE, COMPOSITION COMPRISING THE DERIVATIVE, AND OPTICAL AND ELECTRONIC MEMBER USING THE COMPOSITION Idemitsu Kosan Co., Ltd. (JP) 2008-10-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100274043-A1 ADAMANTYL GROUP-CONTAINING EPOXY-MODIFIED (METH)ACRYLATE AND RESIN COMPOSITION CONTAINING THE SAME TAS2R42, MEP1A, TAS2R41 ALDH1A1 219/4885GLA 4337/4885VDR 1961/4885
US-20090099330-A1 ADAMANTYL GROUP-CONTAINING EPOXY-MODIFIED (METH)ACRYLATE AND RESIN COMPOSITION CONTAINING THE SAME TAS2R42, MEP1A, TAS2R41 ALDH1A1 227/4885GLA 4350/4885VDR 1946/4885
US-20090062481-A1 ADAMANTANE DERIVATIVE, COMPOSITION COMPRISING THE DERIVATIVE, AND OPTICAL AND ELECTRONIC MEMBER USING THE COMPOSITION APP, ADAM17, PSD ALDH1A1 301/4885GLA 481/4885VDR 187/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.