Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.35 |
| ▸ | YEATS4 | O95619 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
| ▸ | SPR | P35270 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19775352 | 0.88 | GABRA5 (0.39) | ALDH1A1NPC1RAB9AKDM4EHDAC1 | |
| SCHEMBL19775117 | 0.86 | NPC1 (0.49) | ALDH1A1NPC1RAB9AKDM4EHDAC1 | |
| SCHEMBL19775142 | 0.85 | YEATS4 (0.46) | ALDH1A1NPC1RAB9AKDM4EHDAC1 | |
| SCHEMBL19775370 | 0.84 | HPGD (0.50) | ALDH1A1NPC1RAB9AHDAC4YEATS4 | |
| SCHEMBL20082245 | 0.83 | P2RY14 (0.39) | ALDH1A1NPC1RAB9AKDM4EHDAC1 | |
| SCHEMBL19775154 | 0.82 | SPR (0.40) | ALDH1A1NPC1RAB9AKDM4EHDAC1 | |
| SCHEMBL19775125 | 0.82 | SPR (0.39) | ALDH1A1NPC1RAB9AKDM4EHDAC1 | |
| SCHEMBL8104105 | 0.81 | GABRA5 (0.43) | ALDH1A1NPC1RAB9AKDM4EHDAC1 | |
| SCHEMBL21230172 | 0.81 | HDAC1 (0.36) | ALDH1A1NPC1RAB9AKDM4EHDAC1 | |
| SCHEMBL19775156 | 0.80 | SPR (0.38) | ALDH1A1NPC1RAB9AKDM4EHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3311813-A1 | THERAPEUTIC ISOXAZOLE COMPOUNDS | Dart Neuroscience (Cayman) Ltd (KY) | 2018-04-25 | — | — | EP | disclosed |