Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.31 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.30 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.30 |
| ▸ | TUBB | P07437 | 1/20 | 0.30 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.30 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.30 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.30 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.30 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30786251 | 0.75 | LTA4H (0.43) | SMN1; SMN2 | |
| SCHEMBL12036828 | 0.75 | TUBB4A (0.36) | ALDH1A1MAPTSMN1; SMN2TUBB1TUBB4A | |
| SCHEMBL2726596 | 0.73 | CA12 (0.42) | CA12CA1CA9CA2CA7 | |
| SCHEMBL932015 | 0.73 | KDM4E (0.38) | — | |
| SCHEMBL18951811 | 0.73 | TUBB4A (0.51) | CA12CA1CA9CA2CA7 | |
| SCHEMBL10841695 | 0.72 | P4HTM (0.54) | MAPTSMN1; SMN2 | |
| SCHEMBL30786097 | 0.71 | HRH3 (0.51) | — | |
| SCHEMBL30648147 | 0.71 | APP (0.51) | ALDH1A1POLBMAPTSMN1; SMN2 | |
| SCHEMBL27081518 | 0.71 | APP (0.51) | ALDH1A1POLBMAPTSMN1; SMN2 | |
| SCHEMBL16248104 | 0.71 | SRD5A1 (0.33) | MAPTTUBB1TUBB4ATUBBTUBA3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3312170-A1 | 1,4-DI-SUBSTITUTED IMIDAZOLE DERIVATIVE | Sumitomo Dainippon Pharma Co., Ltd. (JP) | 2018-04-25 | — | — | EP | disclosed |