Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.53 |
| ▸ | RAB9A | P51151 | 7/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.51 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21844862 | 0.87 | MEN1 (0.59) | RAB9AKMT2AMEN1KCNK3KCNK9 | |
| SCHEMBL20083991 | 0.82 | GRM4 (0.46) | NPC1RAB9AKMT2AMEN1LMNA | |
| SCHEMBL19157165 | 0.81 | BCHE (0.59) | NPC1RAB9AHPGDKMT2AMEN1 | |
| SCHEMBL21844847 | 0.80 | TMEM97 (0.52) | NPC1RAB9AKMT2AMEN1KCNK3 | |
| SCHEMBL19157637 | 0.77 | NPC1 (0.50) | NPC1RAB9AHPGDKMT2AMEN1 | |
| SCHEMBL15276892 | 0.76 | MAPT (0.56) | NPC1RAB9AHPGDKMT2AMEN1 | |
| SCHEMBL21844850 | 0.76 | KDR (0.43) | NPC1RAB9AKMT2AMEN1KCNK3 | |
| SCHEMBL20083999 | 0.76 | KDR (0.43) | KMT2AMEN1TSHRLMNA | |
| SCHEMBL21844909 | 0.75 | KMT2A (0.40) | NPC1RAB9AHPGDKMT2AMEN1 | |
| SCHEMBL20083950 | 0.74 | KDR (0.46) | KMT2AMEN1TSHRLMNAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3312160-B1 | HEPATITIS B ANTIVIRAL AGENTS | NOVIRA THERAPEUTICS INC (US) | 2020-03-18 | — | — | EP | disclosed |
| EP-3312160-A1 | HEPATITIS B ANTIVIRAL AGENTS | Novira Therapeutics Inc. (US) | 2018-04-25 | — | — | EP | disclosed |