Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.59 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.59 |
| ▸ | KCNK3 | O14649 | 11/20 | 0.56 |
| ▸ | KCNK9 | Q9NPC2 | 8/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20083997 | 0.87 | NPC1 (0.53) | MEN1KMT2AKCNK3KCNK9POLB | |
| SCHEMBL1696311 | 0.81 | MEN1 (0.70) | MEN1KMT2ARXFP1KCNK3KCNK9 | |
| SCHEMBL21844847 | 0.81 | TMEM97 (0.52) | MEN1KMT2AKCNK3KCNK9RAB9A | |
| SCHEMBL20083991 | 0.79 | GRM4 (0.46) | MEN1KMT2APOLBRAB9ALMNA | |
| SCHEMBL15676738 | 0.79 | MEN1 (0.74) | MEN1KMT2ARXFP1KCNK3KCNK9 | |
| SCHEMBL17052993 | 0.77 | MEN1 (0.72) | MEN1KMT2ARXFP1KCNK3KCNK9 | |
| SCHEMBL21377635 | 0.77 | KCNK3 (0.77) | MEN1KMT2ARXFP1KCNK3KCNK9 | |
| SCHEMBL4253897 | 0.76 | KCNK3 (0.93) | MEN1KMT2ARXFP1KCNK3KCNK9 | |
| SCHEMBL15276891 | 0.76 | LMNA (0.70) | MEN1KMT2ARXFP1KCNK3KCNK9 | |
| SCHEMBL21844906 | 0.76 | BCHE (0.49) | MEN1KMT2AKCNK3KCNK9KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3312160-B1 | HEPATITIS B ANTIVIRAL AGENTS | NOVIRA THERAPEUTICS INC (US) | 2020-03-18 | — | — | EP | disclosed |