Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.40 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.40 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 3/20 | 0.38 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.37 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21844908 | 0.85 | KDM1A (0.48) | KMT2AMEN1OPRM1OPRD1OPRK1 | |
| SCHEMBL20084044 | 0.85 | MAOB (0.44) | NPC1RAB9AKDM1ALMNAMAOB | |
| SCHEMBL20084043 | 0.83 | SMN1; SMN2 (0.47) | KMT2AMEN1OPRM1OPRD1OPRK1 | |
| SCHEMBL19157637 | 0.83 | NPC1 (0.50) | KMT2AMEN1HDAC8HDAC6L3MBTL1 | |
| SCHEMBL15276907 | 0.76 | SLC6A9 (0.46) | KMT2AMEN1SLC6A9HDAC8HDAC6 | |
| SCHEMBL20083997 | 0.75 | NPC1 (0.53) | KMT2AMEN1L3MBTL1NPC1RAB9A | |
| SCHEMBL21844837 | 0.73 | HTR2A (0.47) | OPRM1NPC1RAB9AACKR3 | |
| SCHEMBL30037664 | 0.71 | MEN1 (0.69) | KMT2AMEN1HTR2BNPC1RAB9A | |
| SCHEMBL15838798 | 0.71 | ROCK2 (0.52) | KMT2AMEN1L3MBTL1LMNA | |
| Hydrochloric Acid SCHEMBL15826223 | 0.71 | ROCK2 (0.51) | KMT2AMEN1L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3312160-B1 | HEPATITIS B ANTIVIRAL AGENTS | NOVIRA THERAPEUTICS INC (US) | 2020-03-18 | — | — | EP | disclosed |