Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 1/20 | 0.50 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.43 |
| ▸ | SLC9A2 | Q9UBY0 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31400646 | 1.00 | ACLY (0.50) | ACLYSLC9A1SLC9A2PARP1PTK2B | |
| SCHEMBL2778224 | 0.84 | ACLY (0.51) | ACLYPARP1PTK2BAR | |
| SCHEMBL15836200 | 0.84 | CMA1 (0.43) | PTK2B | |
| SCHEMBL2593426 | 0.84 | PTK2B (0.58) | ACLYPTK2B | |
| SCHEMBL3283017 | 0.83 | SLC9A1 (0.46) | SLC9A1SLC9A2PARP1 | |
| SCHEMBL7832481 | 0.82 | SLC9A1 (0.66) | SLC9A1SLC9A2 | |
| SCHEMBL19157383 | 0.82 | PTK2B (0.43) | PTK2B | |
| SCHEMBL9900899 | 0.82 | PTK2B (0.42) | SLC9A1SLC9A2PTK2B | |
| SCHEMBL16990464 | 0.80 | SLC9A1 (0.44) | SLC9A1SLC9A2PARP1 | |
| SCHEMBL31401329 | 0.80 | ALDH1A1 (0.51) | SLC9A1SLC9A2PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3312160-B1 | HEPATITIS B ANTIVIRAL AGENTS | NOVIRA THERAPEUTICS INC (US) | 2020-03-18 | — | — | EP | disclosed |
| EP-3312160-A1 | HEPATITIS B ANTIVIRAL AGENTS | Novira Therapeutics Inc. (US) | 2018-04-25 | — | — | EP | disclosed |