Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21970598 | 0.71 | NOD1 (0.38) | LMNATSHRALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL21970727 | 0.58 | NOD1 (0.43) | LMNATSHRALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL5931251 | 0.58 | SMN1; SMN2 (0.69) | LMNATSHRALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL3235436 | 0.58 | EGFR (0.55) | LMNATSHRALDH1A1L3MBTL1KMT2A | |
| SCHEMBL6468156 | 0.58 | ALDH1A1 (0.69) | LMNATSHRALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL28405273 | 0.57 | EGFR (0.60) | LMNATSHRALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL8545310 | 0.57 | EGFR (0.60) | LMNATSHRALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL26981518 | 0.57 | HDAC1 (0.49) | LMNAALDH1A1L3MBTL1SMN1; SMN2MEN1 | |
| SCHEMBL28687948 | 0.57 | SMN1; SMN2 (0.67) | LMNATSHRALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL6034081 | 0.57 | CA1 (0.74) | CA1CA2CA9IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3312172-A1 | AMINOPYRAZOLE DERIVATIVES | Chugai Seiyaku Kabushiki Kaisha (JP) | 2018-04-25 | — | — | EP | disclosed |