SCHEMBL2008693

SCHEMBL2008693

C=C(CCCCBr)C(=O)O

nearest known ligand 0.42

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TBXAS1 P24557 2/20 0.41
LMNA P02545 2/20 0.35
TET2 Q6N021 5/20 0.34
TET3 O43151 1/20 0.34
TET1 Q8NFU7 1/20 0.34
TSHR P16473 2/20 0.33
GRIK1 P39086 1/20 0.33
GRIK2 Q13002 1/20 0.33
GRM1 Q13255 1/20 0.33
GRM2 Q14416 1/20 0.33
NFKB1 P19838 1/20 0.33
PMP22 Q01453 1/20 0.33
ALOX15 P16050 1/20 0.33
HSD17B10 Q99714 1/20 0.33
THRB P10828 1/20 0.30
FNTA P49354 1/20 0.30
FNTB P49356 1/20 0.30
PGGT1B P53609 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8624374 0.98 TBXAS1 (0.43) TBXAS1LMNATET2TET3TET1
SCHEMBL982293 0.98 TBXAS1 (0.43) TBXAS1LMNATET2TET3TET1
SCHEMBL6865841 0.98 TBXAS1 (0.43) TBXAS1LMNATET2TET3TET1
SCHEMBL2392849 0.98 TBXAS1 (0.43) TBXAS1LMNATET2TET3TET1
SCHEMBL2770074 0.98 TBXAS1 (0.43) TBXAS1LMNATET2TET3TET1
SCHEMBL6865805 0.98 TBXAS1 (0.43) TBXAS1LMNATET2TET3TET1
SCHEMBL6862064 0.98 TBXAS1 (0.43) TBXAS1LMNATET2TET3TET1
SCHEMBL6858104 0.98 TBXAS1 (0.43) TBXAS1LMNATET2TET3TET1
SCHEMBL449324 0.92
SCHEMBL2025802 0.87 TBXAS1 (0.47) TBXAS1LMNATET2TET3TET1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1242516-B1 PREPARATION OF FUNCTIONAL POLYMERIC SURFACE COMMW SCIENT IND RES ORG (AU) 2004-08-25 EP claimed
US-9103965-B2 Amphiphilic siloxane-containing vinylic monomers and uses thereof NOVARTIS AG (CH) 2015-08-11 US disclosed
US-20140171542-A1 AMPHIPHILIC SILOXANE-CONTAINING VINYLIC MONOMERS AND USES THEREOF NOVARTIS AG (CH) 2014-06-19 US disclosed
US-7960026-B2 Organic-inorganic composite particle and process for preparation thereof ROHM AND HAAS COMPANY (US) 2011-06-14 US disclosed
US-20090017304-A1 Organic-inorganic composite particle and process for preparation thereof KOLLER ANNE DENISE 2009-01-15 US disclosed
US-7265166-B2 Aqueous polymer composition ROHM AND HAAS COMPANY (US) 2007-09-04 US disclosed
US-20060189748-A1 AQUEOUS POLYMERIC COMPOSITION CONTAINING POLYMERIC NANOPARTICLES AND TREATMENTS PREPARED THEREFROM ROHM AND HAAS COMPANY 2006-08-24 US disclosed
US-7091275-B1 Aqueous polymeric composition containing polymeric nanoparticles and treatments prepared therefrom ROHM AND HAAS COMPANY (US) 2006-08-15 US disclosed
US-5441731-A A ion exchange resin based on a cationic polymer of an alkyl alkacrylate, a oligoyalkylene glycol dimethacrylate acid and a trialkylammonioalkyl methacrylate; antichloesterol agent SMITHKLINE & FRENCH LABORATORIES LTD. (GB) 1995-08-15 US disclosed
EP-0373852-B1 Compounds SMITH KLINE FRENCH LAB (GB) 1994-10-26 EP disclosed
EP-0373852-A2 Compounds SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) 1990-06-20 EP disclosed