SCHEMBL2392849

SCHEMBL2392849

C=C(CCCCCCCCCCCBr)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TBXAS1 P24557 2/20 0.43
LMNA P02545 3/20 0.38
TSHR P16473 1/20 0.38
NFKB1 P19838 1/20 0.38
PMP22 Q01453 1/20 0.38
TET2 Q6N021 3/20 0.33
TET3 O43151 1/20 0.33
TET1 Q8NFU7 1/20 0.33
THRB P10828 1/20 0.33
FNTA P49354 1/20 0.33
FNTB P49356 1/20 0.33
PGGT1B P53609 1/20 0.33
MAPT P10636 2/20 0.32
L3MBTL1 Q9Y468 2/20 0.32
GRIK1 P39086 1/20 0.32
GRIK2 Q13002 1/20 0.32
GRM1 Q13255 1/20 0.32
GRM2 Q14416 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
ABCC4 O15439 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL982293 1.00 TBXAS1 (0.43) TBXAS1LMNATSHRNFKB1PMP22
SCHEMBL8624374 1.00 TBXAS1 (0.43) TBXAS1LMNATSHRNFKB1PMP22
SCHEMBL6865805 1.00 TBXAS1 (0.43) TBXAS1LMNATSHRNFKB1PMP22
SCHEMBL6858104 1.00 TBXAS1 (0.43) TBXAS1LMNATSHRNFKB1PMP22
SCHEMBL6862064 1.00 TBXAS1 (0.43) TBXAS1LMNATSHRNFKB1PMP22
SCHEMBL2770074 1.00 TBXAS1 (0.43) TBXAS1LMNATSHRNFKB1PMP22
SCHEMBL6865841 1.00 TBXAS1 (0.43) TBXAS1LMNATSHRNFKB1PMP22
SCHEMBL2008693 0.98 TBXAS1 (0.41) TBXAS1LMNATSHRNFKB1PMP22
SCHEMBL449324 0.90
SCHEMBL1860769 0.87 TBXAS1 (0.50) TBXAS1LMNATSHRNFKB1PMP22

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1242516-B1 PREPARATION OF FUNCTIONAL POLYMERIC SURFACE COMMW SCIENT IND RES ORG (AU) 2004-08-25 EP claimed
CN-110358400-B Water-based quick-drying coil steel coating based on monodisperse polyacrylic resin and preparation method thereof 上海工程技术大学 2021-04-09 CN disclosed
EP-3049178-B1 BICONTINUOUS MICROEMULSION POLYMERIZED COATING FOR WATER TREATMENT HOCHSCHULE KARLSRUHE TECHNIK UND WIRTSCH (DE) 2020-04-08 EP disclosed
US-9837181-B2 Processes for nanoparticle dispersions with ionic liquid-based stabilizers EASTERN MICHIGAN UNIVERSITY (US) 2017-12-05 US disclosed
EP-3049178-A2 BICONTINUOUS MICROEMULSION POLYMERIZED COATING FOR WATER TREATMENT Hochschule Karlsruhe Technik und Wirtschaft (DE) 2016-08-03 EP disclosed
US-9040602-B2 Dental materials on the basis of highly acidic polymerizable bisphosphonic acids IVOCLAR VIVADENT AG (LI) 2015-05-26 US disclosed
US-20150086721-A1 PROCESSES FOR NANOPARTICLE DISPERSIONS WITH IONIC LIQUID-BASED STABILIZERS EASTERN MICHIGAN UNIVERSITY 2015-03-26 US disclosed
US-8920682-B2 Nanoparticle dispersions with ionic liquid-based stabilizers EASTERN MICHIGAN UNIVERSITY (US) 2014-12-30 US disclosed
US-20140296364-A1 Dental Materials on the Basis of Highly Acidic Polymerizable Bisphosphonic Acids IVOCLAR VIVADENT AG (LI) 2014-10-02 US disclosed
EP-2755624-A1 DENTAL MATERIALS ON THE BASIS OF HIGHLY ACIDIC POLYMERISABLE BISPHOSPHONIC ACIDS Ivoclar Vivadent AG (LI) 2014-07-23 EP disclosed
US-20110233458-A1 Nanoparticle dispersions with ionic liquid-based stabilizers EASTERN MICHIGAN UNIVERSITY Office of Research Development (US) 2011-09-29 US disclosed
US-7759401-B2 Nanoporous and microporous solvogels and nanolatexes by microemulsion polymerization EASTERN MICHIGAN UNIVERSITY (US) 2010-07-20 US disclosed
US-20090176915-A1 NANOPOROUS AND MICROPOROUS SOLVOGELS AND NONOLATEXES BY MICROEMULSION POLYMERIZATION EASTERN MICHIGAN UNIVERSITY 2009-07-09 US disclosed
US-5441731-A A ion exchange resin based on a cationic polymer of an alkyl alkacrylate, a oligoyalkylene glycol dimethacrylate acid and a trialkylammonioalkyl methacrylate; antichloesterol agent SMITHKLINE & FRENCH LABORATORIES LTD. (GB) 1995-08-15 US disclosed
EP-0460496-B1 Tetra-amino-anthraquinone dyes BASF AG (DE) 1994-11-30 EP disclosed
EP-0373852-B1 Compounds SMITH KLINE FRENCH LAB (GB) 1994-10-26 EP disclosed
EP-0260687-B1 LIQUID-CRYSTALLINE COPOLYMERS BASF Aktiengesellschaft (DE) 1991-12-18 EP disclosed
EP-0460496-A1 Tetra-amino-anthraquinone dyes BASF Aktiengesellschaft (DE) 1991-12-11 EP disclosed
EP-0373852-A2 Compounds SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) 1990-06-20 EP disclosed
EP-0260687-A2 Liquid-crystalline copolymers BASF Aktiengesellschaft (DE) 1988-03-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140296364-A1 Dental Materials on the Basis of Highly Acidic Polymerizable Bisphosphonic Acids PHOSPHO1, PTK2, ITGA1 TBXAS1 2450/4885LMNA 3778/4885TSHR 4440/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.