Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | TET2 | Q6N021 | 3/20 | 0.33 |
| ▸ | TET3 | O43151 | 1/20 | 0.33 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | FNTA | P49354 | 1/20 | 0.33 |
| ▸ | FNTB | P49356 | 1/20 | 0.33 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.32 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.32 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2392849 | 1.00 | TBXAS1 (0.43) | TBXAS1LMNATSHRNFKB1PMP22 | |
| SCHEMBL982293 | 1.00 | TBXAS1 (0.43) | TBXAS1LMNATSHRNFKB1PMP22 | |
| SCHEMBL6865805 | 1.00 | TBXAS1 (0.43) | TBXAS1LMNATSHRNFKB1PMP22 | |
| SCHEMBL6858104 | 1.00 | TBXAS1 (0.43) | TBXAS1LMNATSHRNFKB1PMP22 | |
| SCHEMBL6862064 | 1.00 | TBXAS1 (0.43) | TBXAS1LMNATSHRNFKB1PMP22 | |
| SCHEMBL2770074 | 1.00 | TBXAS1 (0.43) | TBXAS1LMNATSHRNFKB1PMP22 | |
| SCHEMBL6865841 | 1.00 | TBXAS1 (0.43) | TBXAS1LMNATSHRNFKB1PMP22 | |
| SCHEMBL2008693 | 0.98 | TBXAS1 (0.41) | TBXAS1LMNATSHRNFKB1PMP22 | |
| SCHEMBL449324 | 0.90 | — | — | |
| SCHEMBL1860769 | 0.87 | TBXAS1 (0.50) | TBXAS1LMNATSHRNFKB1PMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0476187-B1 | A highly photosensitive imaging element based on a photosensitive resin | AGFA GEVAERT NV (BE) | 1998-05-20 | — | — | EP | disclosed |
| US-5441731-A | A ion exchange resin based on a cationic polymer of an alkyl alkacrylate, a oligoyalkylene glycol dimethacrylate acid and a trialkylammonioalkyl methacrylate; antichloesterol agent | SMITHKLINE & FRENCH LABORATORIES LTD. (GB) | 1995-08-15 | — | — | US | disclosed |
| EP-0373852-B1 | Compounds | SMITH KLINE FRENCH LAB (GB) | 1994-10-26 | — | — | EP | disclosed |
| EP-0476187-A1 | A highly photosensitive imaging element based on a photosensitive resin | AGFA-GEVAERT N.V. (BE) | 1992-03-25 | — | — | EP | disclosed |
| EP-0373852-A2 | Compounds | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1990-06-20 | — | — | EP | disclosed |