Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | TET2 | Q6N021 | 3/20 | 0.33 |
| ▸ | TET3 | O43151 | 1/20 | 0.33 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | FNTA | P49354 | 1/20 | 0.33 |
| ▸ | FNTB | P49356 | 1/20 | 0.33 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.32 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.32 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2392849 | 1.00 | TBXAS1 (0.43) | TBXAS1LMNATSHRNFKB1PMP22 | |
| SCHEMBL982293 | 1.00 | TBXAS1 (0.43) | TBXAS1LMNATSHRNFKB1PMP22 | |
| SCHEMBL8624374 | 1.00 | TBXAS1 (0.43) | TBXAS1LMNATSHRNFKB1PMP22 | |
| SCHEMBL6858104 | 1.00 | TBXAS1 (0.43) | TBXAS1LMNATSHRNFKB1PMP22 | |
| SCHEMBL6862064 | 1.00 | TBXAS1 (0.43) | TBXAS1LMNATSHRNFKB1PMP22 | |
| SCHEMBL2770074 | 1.00 | TBXAS1 (0.43) | TBXAS1LMNATSHRNFKB1PMP22 | |
| SCHEMBL6865841 | 1.00 | TBXAS1 (0.43) | TBXAS1LMNATSHRNFKB1PMP22 | |
| SCHEMBL2008693 | 0.98 | TBXAS1 (0.41) | TBXAS1LMNATSHRNFKB1PMP22 | |
| SCHEMBL449324 | 0.90 | — | — | |
| SCHEMBL1860769 | 0.87 | TBXAS1 (0.50) | TBXAS1LMNATSHRNFKB1PMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242516-B1 | PREPARATION OF FUNCTIONAL POLYMERIC SURFACE | COMMW SCIENT IND RES ORG (AU) | 2004-08-25 | — | — | EP | claimed |
| US-10590218-B2 | Polymer compositions with enhanced radiopacity | ENDOSHAPE, INC. (US) | 2020-03-17 | — | — | US | disclosed |
| EP-2968620-B1 | POLYMER COMPOSITIONS WITH ENHANCED RADIOPACITY | ENDOSHAPE INC (US) | 2019-02-13 | — | — | EP | disclosed |
| US-20160024239-A1 | POLYMER COMPOSITIONS WITH ENHANCED RADIOPACITY | EMBOLIZATION, INC. | 2016-01-28 | — | — | US | disclosed |
| EP-2968620-A1 | POLYMER COMPOSITIONS WITH ENHANCED RADIOPACITY | Endoshape, Inc. (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014200594-A1 | POLYMER COMPOSITIONS WITH ENHANCED RADIOPACITY | ENDOSHAPE, INC. (US) | 2014-12-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10590218-B2 | Polymer compositions with enhanced radiopacity | PARN, PARG, RAD50 | TBXAS1 2363/4885LMNA 1418/4885TSHR 4094/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.