SCHEMBL2008989

SCHEMBL2008989

OCCc1ccoc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2011542 0.86
SCHEMBL6519956 0.84 NAAA (0.44)
SCHEMBL8670495 0.84 ALOX5 (0.43)
SCHEMBL358851 0.79
SCHEMBL356407 0.75
SCHEMBL7341457 0.75
SCHEMBL11453935 0.75
SCHEMBL983235 0.75
SCHEMBL2008986 0.75
SCHEMBL1191598 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118136842-A Negative electrode material and preparation method and application thereof 湖南中科星城石墨有限公司 2024-06-04 CN claimed
US-10071501-B2 Chemically modified wood and non-wood products and methods for the production thereof Zhang, Ling Ling (AU) 2018-09-11 US claimed
EP-3129199-A1 CHEMICALLY MODIFIED WOOD AND NON-WOOD PRODUCTS AND METHODS FOR THE PRODUCTION THEREOF Hermescec, Branko (CN) 2017-02-15 EP claimed
US-20160144531-A1 CHEMICALLY MODIFIED WOOD AND NON-WOOD PRODUCTS AND METHODS FOR THE PRODUCTION THEREOF HERMESCEC, BRANKO (CN) 2016-05-26 US claimed
US-20250326744-A1 PIPERAZINE DERIVATIVE OR SALT THEREOF, AND PHARMACEUTICAL COMPOSITION FUJIFILM CORPORATION (JP) 2025-10-23 US disclosed
CN-119816484-A Novel piperazine derivative or salt thereof and pharmaceutical composition 富士胶片株式会社 2025-04-11 CN disclosed
EP-4423069-A1 INHIBITORS OF HIF-2ALPHA AND METHODS OF USE THEREOF Arcus Biosciences, Inc. (US) 2024-09-04 EP disclosed
US-12071411-B2 Inhibitors of HIF-2α and methods of use thereof ARCUS BIOSCIENCES, INC. (US) 2024-08-27 US disclosed
CN-112789276-B Analgesic compounds, process for their preparation and their use in medicine 上海海雁医药科技有限公司 2024-07-30 CN disclosed
CN-118176183-A HIF-2 alpha inhibitors and methods of use thereof 艾库斯生物科学有限公司 2024-06-11 CN disclosed
CN-118136842-A Negative electrode material and preparation method and application thereof 湖南中科星城石墨有限公司 2024-06-04 CN disclosed
WO-2024043334-A1 NOVEL PIPERAZINE DERIVATIVE OR SALT THEREOF AND PHARMACEUTICAL COMPOSITION 富士フイルム株式会社 2024-02-29 WO disclosed
EP-1757594-A1 QUINAZOLINE DERIVATIVE BANYU PHARMACEUTICAL CO., LTD. (JP) 2007-02-28 EP disclosed
US-20050171094-A1 Pyrrolopyrimidine derivatives TEIJIN, LIMITED (JP) 2005-08-04 US disclosed
EP-1477490-A1 PYRROLOPYRIMIDINE DERIVATIVE TEIJIN LIMITED (JP) 2004-11-17 EP disclosed
US-6462207-B1 WHICH UPON FURTHER CHEMICAL MODIFICATION ARE USEFUL IN BIOMEDICAL APPLICATIONS, PERMIT THE SYNTHESIS OF NEW POLYMERS, MAY BE USED AS INTERMEDIATES IN THE PREPARATION OF COMPOSITIONS POSSESSING PROPERTIES OF INTEREST SOUTHWEST MISSOURI STATE UNIVERSITY 2002-10-08 US disclosed
US-5998433-A THERAPY FOR HYPERLIPIDEMIA; ATHEROSCLEROSIS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1999-12-07 US disclosed
CN-1160403-A Substd. heterobicyclic alkyl amines and their use as squalene oxide cyclase inhibitors TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1997-09-24 CN disclosed
EP-0785939-A1 SUBSTITUTED HETEROBICYCLIC ALKYL AMINES AND THEIR USE AS SQUALENE OXIDE CYCLASE INHIBITORS Takeda Chemical Industries, Ltd. (JP) 1997-07-30 EP disclosed
WO-1996011201-A1 SUBSTITUTED HETEROBICYCLIC ALKYL AMINES AND THEIR USE AS SQUALENE OXIDE CYCLASE INHIBITORS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1996-04-18 WO disclosed