SCHEMBL6519956

SCHEMBL6519956

OCCCCc1ccoc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.44
CA2 P00918 3/20 0.40
ALOX5 P09917 1/20 0.39
PTPN2 P17706 2/20 0.38
PTPN1 P18031 2/20 0.38
DUSP3 P51452 2/20 0.38
CETP P11597 1/20 0.38
CYP4F2 P78329 2/20 0.38
CYP4A11 Q02928 2/20 0.38
NR1H4 Q96RI1 1/20 0.36
CNR2 P34972 2/20 0.35
FAAH O00519 2/20 0.33
SLC1A3 P43003 1/20 0.33
SLC1A2 P43004 1/20 0.33
SLC1A1 P43005 1/20 0.33
MEN1 O00255 1/20 0.33
ALDH1A1 P00352 1/20 0.33
MAPT P10636 1/20 0.33
RECQL P46063 1/20 0.33
BLM P54132 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2011542 0.93
SCHEMBL2008989 0.84
1,5-Pentanediol SCHEMBL29013567 0.83 ALOX5 (0.39) NAAACA2ALOX5PTPN2PTPN1
SCHEMBL981066 0.80 CETP (0.50) CETPCNR2FAAHMEN1ALDH1A1
SCHEMBL981638 0.78 CETP (0.53) NAAACETPCNR2ALDH1A1HIF1A
SCHEMBL1532421 0.78 CETP (0.53) NAAACETPCNR2ALDH1A1HIF1A
SCHEMBL827036 0.78 NAAA (0.41) NAAAALOX5PTPN2PTPN1DUSP3
SCHEMBL981165 0.78 CETP (0.53) NAAACETPCNR2ALDH1A1HIF1A
SCHEMBL1532409 0.78 CETP (0.53) NAAACETPCNR2ALDH1A1HIF1A
SCHEMBL6519953 0.78 NAAA (0.44) NAAAALOX5PTPN2PTPN1DUSP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103459359-A Polyols and their use in hydrocarbon lubricating and drilling fluids LORD CORP 2013-12-18 CN claimed
EP-2670726-A1 POLYOLS AND THEIR USE IN HYDROCARBON LUBRICATING AND DRILLING FLUIDS Lord Corporation (US) 2013-12-11 EP claimed
US-20120202723-A1 POLYOLS AND THEIR USE IN HYDROCARBON LUBRICATING AND DRILLING FLUIDS LORD CORPORATION 2012-08-09 US claimed
WO-2012106597-A1 POLYOLS AND THEIR USE IN HYDROCARBON LUBRICATING AND DRILLING FLUIDS LORD CORPORATION (US) 2012-08-09 WO claimed
CN-103459359-A Polyols and their use in hydrocarbon lubricating and drilling fluids LORD CORP 2013-12-18 CN disclosed
EP-2670726-A1 POLYOLS AND THEIR USE IN HYDROCARBON LUBRICATING AND DRILLING FLUIDS Lord Corporation (US) 2013-12-11 EP disclosed
US-20120202723-A1 POLYOLS AND THEIR USE IN HYDROCARBON LUBRICATING AND DRILLING FLUIDS LORD CORPORATION 2012-08-09 US disclosed
WO-2012106597-A1 POLYOLS AND THEIR USE IN HYDROCARBON LUBRICATING AND DRILLING FLUIDS LORD CORPORATION (US) 2012-08-09 WO disclosed
US-20050171094-A1 Pyrrolopyrimidine derivatives TEIJIN, LIMITED (JP) 2005-08-04 US disclosed
EP-1477490-A1 PYRROLOPYRIMIDINE DERIVATIVE TEIJIN LIMITED (JP) 2004-11-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120202723-A1 POLYOLS AND THEIR USE IN HYDROCARBON LUBRICATING AND DRILLING FLUIDS SCD, MRE11, POLH NAAA 956/4885CA2 4664/4885ALOX5 20/4885
US-20050171094-A1 Pyrrolopyrimidine derivatives GSK3B, GSK3A, GSKIP NAAA 3876/4885CA2 1302/4885ALOX5 4653/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.