Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.45 |
| ▸ | ADH1B | P00325 | 1/20 | 0.45 |
| ▸ | ADH1C | P00326 | 1/20 | 0.45 |
| ▸ | ADH1A | P07327 | 1/20 | 0.45 |
| ▸ | ADH4 | P08319 | 1/20 | 0.45 |
| ▸ | ADH7 | P40394 | 1/20 | 0.45 |
| ▸ | S1PR2 | O95136 | 6/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 6/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 6/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.39 |
| ▸ | KDM5A | P29375 | 3/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.38 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20091176 | 1.00 | ALDH1A1 (0.54) | ALDH1A1TSHREPHX1ADH1BADH1C | |
| SCHEMBL20091179 | 1.00 | ALDH1A1 (0.54) | ALDH1A1TSHREPHX1ADH1BADH1C | |
| SCHEMBL20091178 | 1.00 | ALDH1A1 (0.54) | ALDH1A1TSHREPHX1ADH1BADH1C | |
| SCHEMBL20091205 | 1.00 | ALDH1A1 (0.54) | ALDH1A1TSHREPHX1ADH1BADH1C | |
| SCHEMBL20091177 | 1.00 | ALDH1A1 (0.54) | ALDH1A1TSHREPHX1ADH1BADH1C | |
| SCHEMBL20091166 | 1.00 | ALDH1A1 (0.54) | ALDH1A1TSHREPHX1ADH1BADH1C | |
| SCHEMBL21498012 | 0.91 | ALDH1A1 (0.59) | ALDH1A1TSHREPHX1ADH1BADH1C | |
| SCHEMBL18073416 | 0.91 | DNM1 (0.48) | ALDH1A1TSHREPHX1ADH1BADH1C | |
| SCHEMBL26144828 | 0.89 | ALDH1A1 (0.62) | ALDH1A1TSHREPHX1ADH1BADH1C | |
| SCHEMBL25868228 | 0.89 | TSHR (0.48) | ALDH1A1TSHREPHX1ADH1BADH1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10301254-B2 | Substituted polycationic multi-quaternary ammonium salts as antimicrobial agents | Temple University—Of the Commonwealth System of Higher Education (US) | 2019-05-28 | — | — | US | disclosed |
| US-20180111893-A1 | POLYCATIONIC AMPHIPHILES AND POLYMERS THEREOF AS ANTIMICROBIAL AGENTS AND METHODS USING SAME | Temple University--of the Commonwealth System of Higher Education | 2018-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180111893-A1 | POLYCATIONIC AMPHIPHILES AND POLYMERS THEREOF AS ANTIMICROBIAL AGENTS AND METHODS USING SAME | PHOSPHO1, PCNA, PUF60 | ALDH1A1 4368/4885TSHR 4022/4885EPHX1 1987/4885 |
| US-10301254-B2 | Substituted polycationic multi-quaternary ammonium salts as antimicrobial agents | F7, ABCB11, ARG1 | ALDH1A1 3667/4885TSHR 4104/4885EPHX1 2859/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.