SCHEMBL2009309

SCHEMBL2009309

OCCCC(O)(c1ccc(Cl)cc1)c1ccc(Cl)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCL2 P10415 2/20 0.62
NPSR1 Q6W5P4 5/20 0.47
POLB P06746 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
MEN1 O00255 3/20 0.45
KMT2A Q03164 3/20 0.45
TSHR P16473 1/20 0.45
MAPK1 P28482 1/20 0.45
HIF1A Q16665 1/20 0.45
MIF P14174 1/20 0.42
HTT P42858 3/20 0.42
KIF11 P52732 1/20 0.42
LMNA P02545 3/20 0.40
CYP19A1 P11511 2/20 0.39
PRKACA P17612 2/20 0.37
AKT1 P31749 2/20 0.37
AKT2 P31751 2/20 0.37
AKT3 Q9Y243 2/20 0.37
ROCK2 O75116 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2002860 0.80 BCL2 (0.64) BCL2NPSR1POLBSMN1; SMN2L3MBTL1
SCHEMBL28708715 0.80 BCL2 (0.61) BCL2NPSR1SMN1; SMN2L3MBTL1MEN1
SCHEMBL1984793 0.79 BCL2 (0.41) BCL2NPSR1POLBSMN1; SMN2MAPK1
SCHEMBL2006125 0.78 CHRM4 (0.56) BCL2SMN1; SMN2MAPK1KIF11LMNA
SCHEMBL9196329 0.78 NPSR1 (0.53) BCL2NPSR1POLBSMN1; SMN2L3MBTL1
SCHEMBL23880652 0.78 CYP2D6 (0.44) BCL2NPSR1POLBSMN1; SMN2L3MBTL1
SCHEMBL8313158 0.78 BCL2 (0.40) BCL2NPSR1POLBSMN1; SMN2L3MBTL1
SCHEMBL6048472 0.77 SIGMAR1 (0.58) BCL2SMN1; SMN2MAPK1LMNACHRM3
SCHEMBL7462429 0.76 CCR1 (0.44) BCL2L3MBTL1MEN1KMT2ATSHR
SCHEMBL7606639 0.75 KIF11 (0.46) BCL2NPSR1SMN1; SMN2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7960526-B2 Colorimetric-oxycarbonyl protecting groups for use in organic syntheses BERRY AND ASSOCIATES, INC. (US) 2011-06-14 US disclosed
US-7960526-B2 Colorimetric-oxycarbonyl protecting groups for use in organic syntheses BERRY AND ASSOCIATES, INC. (US) 2011-06-14 US disclosed
US-7960526-B2 Colorimetric-oxycarbonyl protecting groups for use in organic syntheses BERRY AND ASSOCIATES, INC. (US) 2011-06-14 US disclosed
WO-2010114762-A1 COLORIMETRIC-OXYCARBONYL PROTECTING GROUPS FOR USE IN ORGANIC SYNTHESES BERRY AND ASSOCIATES, INC. (US) 2010-10-07 WO disclosed
US-20100249393-A1 COLORIMETRIC-OXYCARBONYL PROTECTING GROUPS FOR USE IN ORGANIC SYNTHESES BERRY AND ASSOCIATES, INC. (US) 2010-09-30 US disclosed
US-20100249393-A1 COLORIMETRIC-OXYCARBONYL PROTECTING GROUPS FOR USE IN ORGANIC SYNTHESES BERRY AND ASSOCIATES, INC. (US) 2010-09-30 US disclosed
US-20100249393-A1 COLORIMETRIC-OXYCARBONYL PROTECTING GROUPS FOR USE IN ORGANIC SYNTHESES BERRY AND ASSOCIATES, INC. (US) 2010-09-30 US disclosed
EP-1235776-B1 TRIPHENYLALKENE DERIVATIVES AND THEIR USE AS SELECTIVE ESTROGEN RECEPTOR MODULATORS HORMOS MEDICAL CORP (FI) 2006-02-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100249393-A1 COLORIMETRIC-OXYCARBONYL PROTECTING GROUPS FOR USE IN ORGANIC SYNTHESES RNGTT, OGA, HCCS BCL2 2618/4885NPSR1 2994/4885POLB 699/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.