SCHEMBL2009378

SCHEMBL2009378

CCCCCCCCCCCC[CH]N

nearest known ligand 0.52

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.52
THRB P10828 1/20 0.50
FAAH O00519 3/20 0.46
TRPV1 Q8NER1 1/20 0.46
DNM1 Q05193 7/20 0.45
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
ALDH1A1 P00352 1/20 0.45
EPHX1 P07099 1/20 0.45
TP53 P04637 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP3A4 P08684 1/20 0.44
CYP2C19 P33261 1/20 0.44
SOAT1 P35610 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4755751 1.00 TSHR (0.52) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL1585548 1.00 TSHR (0.52) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL1948712 1.00 TSHR (0.52) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL2031870 1.00 TSHR (0.52) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL4754038 1.00 TSHR (0.52) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL4755758 1.00 TSHR (0.52) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL4755731 1.00 TSHR (0.52) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL2153463 1.00 TSHR (0.52) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL4755755 1.00 TSHR (0.52) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL4757186 1.00 TSHR (0.52) TSHRTHRBFAAHTRPV1DNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1165491-B1 LTA4 HYDROLASE INHIBITORS INST NAT SANTE RECH MED (FR) 2004-02-11 EP claimed
JP-2003506317-A 2003-02-18 JP claimed
EP-1165491-A1 LTA4 HYDROLASE INHIBITORS INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) 2002-01-02 EP claimed
WO-2000059864-A1 LTA4 HYDROLASE INHIBITORS INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) 2000-10-12 WO claimed
CN-118222271-A Dispersion, composition containing the same, and light conversion layer DIC株式会社 2024-06-21 CN disclosed
CN-118222272-A Dispersion, ink composition containing the same, and light conversion layer DIC株式会社 2024-06-21 CN disclosed
CN-105567397-B Refrigerator oil and working fluid composition for refrigerating machine 吉坤日矿日石能源株式会社 2019-03-08 CN disclosed
CN-104788516-A Microwave synthesis method for dodecyl amino methyl rutin UNIV SICHUAN 2015-07-22 CN disclosed
US-7964683-B2 Biocompatible polymeric compound, biocompatible polymer and polymer particles FUJIFILM CORPORATION (JP) 2011-06-21 US disclosed
CN-101932447-A Hydrophilic element FUJIFILM CORP 2010-12-29 CN disclosed
US-20100016534-A1 BIOCOMPATIBLE POLYMERIC COMPOUND, BIOCOMPATIBLE POLYMER AND POLYMER PARTICLES FUJIFILM CORPORATION (JP) 2010-01-21 US disclosed
WO-2008110612-A2 NOVEL COMPOUNDS AND LUBRICATING COMPOSITIONS COMPRISING THE SAME SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) 2008-09-18 WO disclosed
US-6949281-B1 Varnish composition and liquid-crystal display element CHISSO CORPORATION (JP) 2005-09-27 US disclosed
EP-1165491-B1 LTA4 HYDROLASE INHIBITORS INST NAT SANTE RECH MED (FR) 2004-02-11 EP disclosed
CN-1343216-A Erythromycin derivatives HOBURIKU SEIYAKU CO LTD (JP) 2002-04-03 CN disclosed
EP-1165491-A1 LTA4 HYDROLASE INHIBITORS INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) 2002-01-02 EP disclosed
WO-2000059864-A1 LTA4 HYDROLASE INHIBITORS INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) 2000-10-12 WO disclosed
US-4631272-A N-acylated 1-alkylamino-1-deoxy-ketose derivatives, a process for their preparation and their use BAYER AKTIENGESELLSCHAFT (DE) 1986-12-23 US disclosed
EP-0152856-A2 N-acylated 1-alkylamimo-1-desoxy ketose derivatives, method for their preparation and use BAYER AG (DE) 1985-08-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100016534-A1 BIOCOMPATIBLE POLYMERIC COMPOUND, BIOCOMPATIBLE POLYMER AND POLYMER PARTICLES CD68, ARG1, PUF60 TSHR 3373/4885THRB 4311/4885FAAH 4134/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.