Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | LOX | P28300 | 1/20 | 0.41 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | PRKCQ | Q04759 | 4/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.33 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.32 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.31 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12695292 | 0.86 | RECQL (0.42) | RECQLLOXLOXL3LOXL2TRPA1 | |
| SCHEMBL29828496 | 0.81 | RECQL (0.43) | RECQLLOXLOXL3LOXL2TRPA1 | |
| SCHEMBL30587543 | 0.81 | RECQL (0.43) | RECQLLOXLOXL3LOXL2TRPA1 | |
| SCHEMBL23364969 | 0.81 | RECQL (0.43) | RECQLLOXLOXL3LOXL2TRPA1 | |
| SCHEMBL15391353 | 0.81 | RECQL (0.43) | RECQLLOXLOXL3LOXL2TRPA1 | |
| SCHEMBL30770644 | 0.81 | LOX (0.34) | RECQLLOXLOXL3LOXL2PRKCQ | |
| SCHEMBL20709031 | 0.80 | CCR1 (0.41) | PRKCQ | |
| SCHEMBL803495 | 0.79 | RECQL (0.42) | RECQLLOXLOXL3LOXL2TRPA1 | |
| SCHEMBL31411143 | 0.79 | RECQL (0.42) | RECQLLOXLOXL3LOXL2TRPA1 | |
| SCHEMBL15689789 | 0.79 | RECQL (0.44) | RECQLLOXLOXL3LOXL2TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11330821-B2 | Herbicidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2022-05-17 | — | — | US | disclosed |
| EP-3439477-B1 | MICROBIOCIDAL OXADIAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2020-05-06 | — | — | EP | disclosed |
| US-20180116219-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-05-03 | — | — | US | disclosed |
| US-20180110227-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11330821-B2 | Herbicidal compounds | DDT, HPD, HDHD5 | RECQL 1061/4885LOX 238/4885LOXL3 191/4885 |
| US-20180116219-A1 | HERBICIDAL COMPOUNDS | DDT, HPD, HDHD5 | RECQL 1061/4885LOX 238/4885LOXL3 191/4885 |
| US-20180110227-A1 | HERBICIDAL COMPOUNDS | DDT, HPD, HDHD5 | RECQL 1324/4885LOX 800/4885LOXL3 687/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.