SCHEMBL20709031

SCHEMBL20709031

CCC(C)(CC)c1ccnc(-c2cc(C(C)(CC)CC)ccn2)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 2/20 0.41
CCR5 P51681 2/20 0.41
CCR8 P51685 2/20 0.41
PRKCQ Q04759 6/20 0.35
ESR1 P03372 1/20 0.32
ESR2 Q92731 1/20 0.32
NOS3 P29474 2/20 0.31
NOS2 P35228 2/20 0.31
NOS1 P29475 1/20 0.31
ADRB2 P07550 1/20 0.31
METAP2 P50579 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
KDM5A P29375 1/20 0.30
KDM5B Q9UGL1 1/20 0.30
NPC1 O15118 1/20 0.30
LMNA P02545 1/20 0.30
MAPK1 P28482 1/20 0.30
CASP3 P42574 1/20 0.30
RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26355353 0.86 ASIC3 (0.47) PRKCQMEN1KMT2A
SCHEMBL20283746 0.82 UHRF1 (0.45) CCR1CCR5CCR8PRKCQESR1
SCHEMBL22453287 0.80 MKNK1 (0.43) PRKCQNOS3NOS2ADRB2
SCHEMBL21972604 0.80 ESR1 (0.38) PRKCQESR1ESR2ADRB2MEN1
SCHEMBL20094072 0.80 RECQL (0.41) PRKCQ
SCHEMBL18922136 0.80 NOS3 (0.55) PRKCQNOS3NOS2NOS1MEN1
SCHEMBL14375165 0.80 ALDH1A1 (0.39) PRKCQESR1ESR2MEN1KMT2A
SCHEMBL12928306 0.80 CCR1 (0.39) CCR1CCR5CCR8METAP2MEN1
SCHEMBL347025 0.78 CCR1 (0.48) CCR1CCR5CCR8NOS3NOS2
SCHEMBL29453375 0.78 CCR1 (0.48) CCR1CCR5CCR8NOS3NOS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2353195-B9 PHOTOELECTRIC CONVERSION DEVICES COMPRISING NOVEL LIGANDS AND SENSITIZERS ECOLE POLYTECHNIQUE FED DE LAUSANNE EPFL EPFL TTO (CH) 2019-02-06 EP disclosed