SCHEMBL803495

SCHEMBL803495

CC(C)(C)c1ccnc(Cl)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RECQL P46063 1/20 0.42
LOX P28300 1/20 0.42
LOXL3 P58215 1/20 0.42
LOXL2 Q9Y4K0 1/20 0.42
KIF11 P52732 2/20 0.38
TRPA1 O75762 1/20 0.38
TDP1 Q9NUW8 2/20 0.37
ALDH1A1 P00352 1/20 0.37
HPGD P15428 1/20 0.37
ALOX15 P16050 1/20 0.37
HSD17B10 Q99714 1/20 0.37
SMARCA2 P51531 2/20 0.36
SMARCA4 P51532 2/20 0.36
CCR9 P51686 2/20 0.35
AR P10275 1/20 0.35
IDO1 P14902 1/20 0.35
CYP2C19 P33261 1/20 0.35
CCR1 P32246 1/20 0.34
CCR5 P51681 1/20 0.34
CCR8 P51685 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31411143 1.00 RECQL (0.42) RECQLLOXLOXL3LOXL2KIF11
SCHEMBL24140123 0.83 IDO1 (0.46) RECQLLOXLOXL3LOXL2KIF11
SCHEMBL1437528 0.83 RECQL (0.39) RECQLLOXLOXL3LOXL2TRPA1
SCHEMBL30595892 0.83 RECQL (0.39) RECQLLOXLOXL3LOXL2TRPA1
SCHEMBL15390327 0.83 RECQL (0.44) RECQLLOXLOXL3LOXL2TRPA1
SCHEMBL16446395 0.83 RECQL (0.39) RECQLLOXLOXL3LOXL2TRPA1
SCHEMBL1159842 0.83 LOX (0.44) RECQLLOXLOXL3LOXL2TRPA1
SCHEMBL29537710 0.83 RECQL (0.44) RECQLLOXLOXL3LOXL2TRPA1
SCHEMBL30953393 0.83 LOX (0.44) RECQLLOXLOXL3LOXL2TRPA1
SCHEMBL12695292 0.81 RECQL (0.42) RECQLLOXLOXL3LOXL2TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 403 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118834163-A Synthesis method of 4- (tert-butyl) -2-chloropyridine 安徽大学 2024-10-25 CN claimed
CN-117447513-A White light phosphor powder based on copper-iodine organic hybridization cluster, and preparation method and application thereof 中国科学技术大学 2024-01-26 CN claimed
CN-116261341-B Precursor solution and preparation method thereof, hole transport layer preparation and perovskite solar cell preparation method 西南石油大学 2023-10-03 CN claimed
CN-116261341-A Precursor solution and preparation method thereof, hole transport layer preparation and perovskite solar cell preparation method 西南石油大学 2023-06-13 CN claimed
CN-110041249-A A kind of preparation method of 4- tert-butyl -2- chloropyridine and 4- tert-butyl -2,6- Dichloro-pendin 南京合巨药业有限公司 2019-07-23 CN claimed
US-20260143962-A1 PLATINUM COMPLEX LUMINESCENT MATERIAL AND DEVICE CONTAINING THE SAME GUANGDONG AGLAIA OPTOELECTRONIC MAT CO LTD (CN) 2026-05-21 US disclosed
EP-4741409-A1 FUSED-RING CARBAZOLE TETRADENTATE METAL PLATINUM (II) COMPLEX AND USE THEREOF, AND ELECTRONIC DEVICE Zhejiang University of Technology (CN) 2026-05-13 EP disclosed
US-20260123266-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2026-04-30 US disclosed
EP-4436349-B1 LIGHT-EMITTING DEVICE INCLUDING ORGANOMETALLIC COMPOUND, ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE, AND THE ORGANOMETALLIC COMPOUND SAMSUNG DISPLAY CO LTD (KR) 2026-04-01 EP disclosed
US-20260022294-A1 ORGANOMETALLIC COMPOUND, LIGHT-EMITTING DEVICE AND ELECTRONIC DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2026-01-22 US disclosed
US-20250393389-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2025-12-25 US disclosed
US-12457894-B2 Organometallic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2025-10-28 US disclosed
US-20080188474-A1 e.g. 1-phenyl-N3-(4-(2-(piperidin-1-yl)ethoxy)phenyl)-1H-1,2,4-triazole-3,5-diamine; receptor protein tyrosine kinase (AXL) antagonist; antiinflammatory, anticarcinogenic , antidiabetic agent; rheumatoid arthritis, vascular disease; breast, renal, endometrial, ovarian carcinoma, or myeloid leukemia RIGEL PHARMACEUTICALS, INC. (US) 2008-08-07 US disclosed
US-20080188474-A1 e.g. 1-phenyl-N3-(4-(2-(piperidin-1-yl)ethoxy)phenyl)-1H-1,2,4-triazole-3,5-diamine; receptor protein tyrosine kinase (AXL) antagonist; antiinflammatory, anticarcinogenic , antidiabetic agent; rheumatoid arthritis, vascular disease; breast, renal, endometrial, ovarian carcinoma, or myeloid leukemia RIGEL PHARMACEUTICALS, INC. (US) 2008-08-07 US disclosed
US-20080161345-A1 Aryl Sulfonamides CHEMOCENTRYX, INC. 2008-07-03 US disclosed
US-20080161345-A1 Aryl Sulfonamides CHEMOCENTRYX, INC. 2008-07-03 US disclosed
US-20080119476-A1 Cetp Inhibitors ALI AMJAD 2008-05-22 US disclosed
US-20070037794-A1 4-((5-Chloro-3-(4-methyl-3-trifluoromethylbenzenesulfonylamino)pyridin-2-yl)-oxo-)1H-pyrrolo(2,3-)pyridine;interfere with ligand (monocyte chemoatactic protein-1) for chemokine receptors (CCR2); antiinflammatory agents; immunomodulators; bactericides; viricides; fungicides CHEMOCENTRYX, INC. 2007-02-15 US disclosed
US-20070037794-A1 4-((5-Chloro-3-(4-methyl-3-trifluoromethylbenzenesulfonylamino)pyridin-2-yl)-oxo-)1H-pyrrolo(2,3-)pyridine;interfere with ligand (monocyte chemoatactic protein-1) for chemokine receptors (CCR2); antiinflammatory agents; immunomodulators; bactericides; viricides; fungicides CHEMOCENTRYX, INC. 2007-02-15 US disclosed
EP-0036638-A2 Herbicidal and plant growth regulant 2-sulfinyl and 2-sulfonyl pyridine N-oxides DIAMOND SHAMROCK CORPORATION (US) 1981-09-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250393389-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LBR, LDLR, LIFR RECQL 890/4885LOX 285/4885LOXL3 103/4885
US-20070037794-A1 4-((5-Chloro-3-(4-methyl-3-trifluoromethylbenzenesulfonylamino)pyridin-2-yl)-oxo-)1H-pyrrolo(2,3-)pyridine;interfere with ligand (monocyte chemoatactic protein-1) for chemokine receptors (CCR2); antiinflammatory agents; immunomodulators; bactericides; viricides; fungicides CCR2, CCR1, CCL2 RECQL 4685/4885LOX 2303/4885LOXL3 1688/4885
US-20080119476-A1 Cetp Inhibitors CETP, APOB, MTTP RECQL 2030/4885LOX 1799/4885LOXL3 1793/4885
US-20260143962-A1 PLATINUM COMPLEX LUMINESCENT MATERIAL AND DEVICE CONTAINING THE SAME SLC43A1, CXCR3, SLC39A3 RECQL 1455/4885LOX 2712/4885LOXL3 793/4885
US-20260022294-A1 ORGANOMETALLIC COMPOUND, LIGHT-EMITTING DEVICE AND ELECTRONIC DEVICE GRIN2C, GRIA1, SCO2 RECQL 2721/4885LOX 2432/4885LOXL3 2394/4885
US-12457894-B2 Organometallic compound and organic light-emitting device including the same CRY1, OCIAD1, ORC3 RECQL 2667/4885LOX 1717/4885LOXL3 820/4885
US-20080161345-A1 Aryl Sulfonamides CCR2, CCL2, CX3CR1 RECQL 4662/4885LOX 2634/4885LOXL3 1711/4885
US-20260123266-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LBR, LDLR, GLRB RECQL 2166/4885LOX 400/4885LOXL3 156/4885
US-20080188474-A1 e.g. 1-phenyl-N3-(4-(2-(piperidin-1-yl)ethoxy)phenyl)-1H-1,2,4-triazole-3,5-diamine; receptor protein tyrosine kinase (AXL) antagonist; antiinflammatory, anticarcinogenic , antidiabetic agent; rheumatoid arthritis, vascular disease; breast, renal, endometrial, ovarian carcinoma, or myeloid leukemia AXL, TYRO3, FLT3 RECQL 4232/4885LOX 1765/4885LOXL3 1555/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.