Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ENPP1 | P22413 | 3/20 | 0.42 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.42 |
| ▸ | TYMP | P19971 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL431332 | 1.00 | HIF1A (0.46) | HIF1APOLBENPP1P2RY1TYMP | |
| SCHEMBL30821669 | 1.00 | HIF1A (0.46) | HIF1APOLBENPP1P2RY1TYMP | |
| SCHEMBL10022902 | 1.00 | HIF1A (0.46) | HIF1APOLBENPP1P2RY1TYMP | |
| SCHEMBL887467 | 1.00 | HIF1A (0.46) | HIF1APOLBENPP1P2RY1TYMP | |
| SCHEMBL25754040 | 0.88 | TYMP (0.43) | HIF1APOLBENPP1P2RY1TYMP | |
| SCHEMBL20095278 | 0.87 | HIF1A (0.48) | HIF1APOLBENPP1P2RY1TYMP | |
| SCHEMBL20016922 | 0.87 | HIF1A (0.50) | HIF1APOLBENPP1P2RY1TYMP | |
| SCHEMBL20129803 | 0.85 | HIF1A (0.63) | HIF1A | |
| SCHEMBL10022903 | 0.85 | HIF1A (0.63) | HIF1A | |
| SCHEMBL887520 | 0.85 | HIF1A (0.63) | HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180127816-A1 | METHODS FOR CHEMICAL LIGATION OF NUCLEIC ACIDS | ILLUMINA, INC. (US) | 2018-05-10 | — | — | US | disclosed |
| US-20180127816-A1 | METHODS FOR CHEMICAL LIGATION OF NUCLEIC ACIDS | ILLUMINA, INC. (US) | 2018-05-10 | — | — | US | disclosed |