Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | DAO | P14920 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1231097 | 0.81 | HDAC6 (0.46) | HPGDTHRBALDH1A1HDAC6HDAC3 | |
| SCHEMBL2227006 | 0.78 | CES2 (0.59) | CES2CES1DAOGSK3BKMT2A | |
| SCHEMBL5050913 | 0.76 | CES2 (0.41) | CES2CES1DAOGSK3BKMT2A | |
| SCHEMBL10874696 | 0.73 | GSK3B (0.51) | CES2CES1DAOGSK3BKMT2A | |
| SCHEMBL24198806 | 0.71 | CES2 (0.59) | CES2CES1DAOGSK3BKMT2A | |
| SCHEMBL5050944 | 0.70 | HDAC6 (0.37) | CES2CES1DAOGSK3BKMT2A | |
| SCHEMBL5469523 | 0.69 | CES2 (0.57) | CES2CES1DAOGSK3BKMT2A | |
| SCHEMBL17955222 | 0.69 | ALDH1A1 (0.56) | KMT2AMEN1NPC1LMNASMN1; SMN2 | |
| SCHEMBL17955234 | 0.68 | ALDH1A1 (0.55) | KMT2AMEN1NPC1LMNASMN1; SMN2 | |
| SCHEMBL1244072 | 0.67 | CES2 (0.73) | CES2CES1DAOGSK3BKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7964650-B2 | Carbonyl-functionalized thiophene compounds and related device structures | NORTHWESTERN UNIVERSITY (US) | 2011-06-21 | — | — | US | disclosed |
| US-20090267061-A1 | Carbonyl-Functionalized Thiophene Compounds and Related Device Structures | POLYERA CORPORATION | 2009-10-29 | — | — | US | disclosed |
| US-7528176-B2 | organic field effect transistor device comprising semiconductor component (comprises a composition of thiophene-carbonyl compounds and polymer); enhanced solubility in a solvent and thermal stablity; promote electron and hole mobilities; in thermal analysis, molecular spectroscopy, electrochemistry | NORTHWESTERN UNIVERSITY (US) | 2009-05-05 | — | — | US | disclosed |
| EP-1831205-A1 | CARBONYL-FUNCTIONALIZED THIOPHENE COMPOUNDS AND RELATED DEVICE STRUCTURES | Northwestern University (US) | 2007-09-12 | — | — | EP | disclosed |
| WO-2007050049-A1 | CARBONYL-FUNCTIONALIZED THIOPHENE COMPOUNDS AND RELATED DEVICE STRUCTURES | NORTHWESTERN UNIVERSITY (US) | 2007-05-03 | — | — | WO | disclosed |
| US-20060186401-A1 | Carbonyl-functionalized thiophene compounds and related device structures | POLYERA CORPORATION | 2006-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090267061-A1 | Carbonyl-Functionalized Thiophene Compounds and Related Device Structures | TEC, OR10J3, TRPA1 | CES2 1275/4885CES1 4790/4885DAO 2329/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.