Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | PHGDH | O43175 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ADH1C | P00326 | 1/20 | 0.38 |
| ▸ | ADH1A | P07327 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13036324 | 0.83 | FAAH (0.45) | RAB9AFAAHPHGDHMGLLALDH1A1 | |
| SCHEMBL12783303 | 0.83 | FAAH (0.45) | RAB9AFAAHPHGDHMGLLALDH1A1 | |
| SCHEMBL12234268 | 0.82 | FAAH (0.44) | RAB9AFAAHPHGDHMGLLALDH1A1 | |
| SCHEMBL21666389 | 0.81 | RAB9A (0.42) | RAB9AFAAHPHGDHMGLLALDH1A1 | |
| SCHEMBL16807400 | 0.80 | RAB9A (0.43) | RAB9AFAAHPHGDHMGLLALDH1A1 | |
| SCHEMBL14720161 | 0.79 | RAB9A (0.41) | RAB9AFAAHPHGDHMGLLALDH1A1 | |
| SCHEMBL18907728 | 0.79 | DPP4 (0.40) | RAB9AFAAHPHGDHMGLLALDH1A1 | |
| SCHEMBL12200780 | 0.77 | ALDH1A1 (0.44) | RAB9AFAAHPHGDHMGLLALDH1A1 | |
| SCHEMBL17704770 | 0.73 | FAAH (0.52) | RAB9AFAAHPHGDHMGLLALDH1A1 | |
| SCHEMBL18907738 | 0.72 | RAB9A (0.36) | RAB9AFAAHPHGDHMGLLALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018072602-A1 | THERAPEUTIC COMPOUNDS AND METHODS OF USE THEREOF | GENENTECH, INC. (US) | 2018-04-26 | — | — | WO | disclosed |