SCHEMBL20097219

SCHEMBL20097219

CCOc1ccc(-c2ccc(-c3ccccc3)cc2)c(F)c1F

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FGFR2 P21802 2/20 0.43
FGFR1 P11362 1/20 0.43
PTPRC P08575 1/20 0.42
KDM4E B2RXH2 3/20 0.41
NPC1 O15118 2/20 0.41
RAB9A P51151 2/20 0.41
HSD17B10 Q99714 1/20 0.41
L3MBTL1 Q9Y468 4/20 0.41
ADRB2 P07550 1/20 0.41
ALOX5AP P20292 1/20 0.41
FEN1 P39748 1/20 0.41
ALDH1A1 P00352 5/20 0.40
ADORA3 P0DMS8 1/20 0.40
ADORA2A P29274 1/20 0.40
ADORA1 P30542 1/20 0.40
HDAC1 Q13547 1/20 0.40
HDAC8 Q9BY41 1/20 0.40
HDAC6 Q9UBN7 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP2D6 P10635 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15256185 0.96 L3MBTL1 (0.43) FGFR2FGFR1PTPRCKDM4ENPC1
SCHEMBL21609908 0.95 ADORA1 (0.44) FGFR2FGFR1PTPRCKDM4ENPC1
SCHEMBL21609904 0.89 FGFR2 (0.44) FGFR2FGFR1PTPRCKDM4ENPC1
SCHEMBL9563850 0.86 NQO1 (0.48) FGFR2FGFR1KDM4ENPC1RAB9A
SCHEMBL9492786 0.86 NQO1 (0.48) FGFR2FGFR1KDM4ENPC1RAB9A
SCHEMBL16771252 0.86 ADORA3 (0.42) FGFR2FGFR1PTPRCKDM4ENPC1
SCHEMBL21609902 0.86 KDM4E (0.43) FGFR2FGFR1PTPRCKDM4ENPC1
SCHEMBL9495395 0.86 PTPN11 (0.46) KDM4EL3MBTL1ADRB2ALOX5APFEN1
SCHEMBL8932603 0.86 TAAR1 (0.45) FGFR2FGFR1KDM4EHSD17B10L3MBTL1
SCHEMBL15381834 0.85 FGFR2 (0.39) FGFR2FGFR1PTPRCKDM4EHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230303928-A1 LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL DISPLAY ELEMENT AND LIQUID CRYSTAL DISPLAY SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO.,LTD. (CN) 2023-09-28 US disclosed
US-20230183572-A1 LIQUID CRYSTAL COMPOSITION WITH GOOD FREQUENCY DEPENDENCE AND LIQUID CRYSTAL DISPLAY ELEMENT SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO., LTD. (CN) 2023-06-15 US disclosed
US-20230183573-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO., LTD. (CN) 2023-06-15 US disclosed
US-20230167362-A1 NEGATIVE LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT OR LIQUID CRYSTAL DISPLAY SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MAT CO ITD (CN) 2023-06-01 US disclosed
US-11208395-B2 Compound, liquid crystal medium containing the compound and application thereof SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO., LTD. (CN) 2021-12-28 US disclosed
US-11155752-B2 Liquid crystal composition and display device thereof JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) 2021-10-26 US disclosed
US-20210017450-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE HAVING SAME JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) 2021-01-21 US disclosed
US-10519377-B1 Liquid crystal composition of negative monomer containing cyclopentyl cyclohexenyl and liquid crystal display element or liquid crystal display thereof Shijiazhuang Chengzhi Yonghua Display Material Co., Ltd (CN) 2019-12-31 US disclosed
US-20190345129-A1 COMPOUND, LIQUID CRYSTAL MEDIUM CONTAINING THE COMPOUND AND APPLICATION THEREOF SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO., LTD. (CN) 2019-11-14 US disclosed
US-20190345386-A1 LIQUID CRYSTAL COMPOSITION AND DISPLAY DEVICE THEREOF JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) 2019-11-14 US disclosed
US-10351773-B2 Liquid crystal compounds of cycloalkyl-containing dibenzofuran derivatives, preparation method therefor and use thereof Shijiazhuang Chengzhi Yonghua Display Material Co., Ltd (CN) 2019-07-16 US disclosed
US-20180112132-A1 LIQUID CRYSTAL COMPOUNDS OF CYCLOALKYL-CONTAINING DIBENZOFURAN DERIVATIVES, PREPARATION METHOD THEREFOR AND USE THEREOF SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO.,LTD (CN) 2018-04-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180112132-A1 LIQUID CRYSTAL COMPOUNDS OF CYCLOALKYL-CONTAINING DIBENZOFURAN DERIVATIVES, PREPARATION METHOD THEREFOR AND USE THEREOF CYP4F11, WASF2, NOTUM FGFR2 596/4885FGFR1 454/4885PTPRC 4682/4885
US-20190345129-A1 COMPOUND, LIQUID CRYSTAL MEDIUM CONTAINING THE COMPOUND AND APPLICATION THEREOF ABCG2, TPST2, TST FGFR2 78/4885FGFR1 128/4885PTPRC 2476/4885
US-11208395-B2 Compound, liquid crystal medium containing the compound and application thereof TST, TPST2, ABCG2 FGFR2 70/4885FGFR1 134/4885PTPRC 2311/4885
US-10351773-B2 Liquid crystal compounds of cycloalkyl-containing dibenzofuran derivatives, preparation method therefor and use thereof CYP4F11, WASF2, NOTUM FGFR2 596/4885FGFR1 454/4885PTPRC 4682/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.