SCHEMBL20098709

SCHEMBL20098709

C=CC(=C)N(c1ccc(-c2ccccc2)cc1)c1cccc(-c2ccccc2)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.35
MEN1 O00255 2/20 0.33
ESR1 P03372 2/20 0.33
KMT2A Q03164 2/20 0.33
NPSR1 Q6W5P4 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C9 P11712 1/20 0.33
HSD17B1 P14061 1/20 0.33
HSD17B2 P37059 1/20 0.33
EGFR P00533 1/20 0.33
MGLL Q99685 1/20 0.33
PTGS2 P35354 1/20 0.33
ACMSD Q8TDX5 1/20 0.33
BACE1 P56817 1/20 0.33
ESR2 Q92731 2/20 0.33
KDM4E B2RXH2 1/20 0.33
USP2 O75604 1/20 0.33
ALDH1A1 P00352 1/20 0.33
LMNA P02545 1/20 0.33
HSP90AA1 P07900 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20005325 0.92 NPSR1 (0.39) MEN1KMT2ANPSR1CYP3A4MGLL
SCHEMBL12699618 0.82 NPSR1 (0.46) MEN1KMT2ANPSR1ALDH1A1GAA
SCHEMBL23570956 0.79 HSD17B2 (0.40) HSD17B1HSD17B2EGFRMGLL
SCHEMBL22053435 0.78 ACMSD (0.33) ALOX5EGFRACMSD
SCHEMBL19130293 0.77 KMO (0.34) ALOX5MEN1ESR1KMT2ACYP3A4
SCHEMBL18913688 0.73 MEN1 (0.39) MEN1KMT2AMGLLKDM4EUSP2
SCHEMBL27667245 0.69 KMT2A (0.49) MEN1KMT2ANPSR1HSD17B1HSD17B2
SCHEMBL23108823 0.69 ALDH1A1 (0.48) ALOX5MEN1ESR1KMT2ACYP3A4
SCHEMBL22355482 0.69 ALDH1A1 (0.48) ALOX5MEN1ESR1KMT2ACYP3A4
SCHEMBL24309151 0.69 ALDH1A1 (0.48) ALOX5MEN1ESR1KMT2ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9957441-B2 Amine-based compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2018-05-01 US disclosed