SCHEMBL2009922

SCHEMBL2009922

O=C(Cl)c1cccc(NC(=O)c2ccc(Cl)cc2Cl)c1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 7/20 0.65
KMT2A Q03164 7/20 0.65
MAPT P10636 5/20 0.64
TP53 P04637 3/20 0.64
NPC1 O15118 3/20 0.64
RAB9A P51151 3/20 0.64
TDP1 Q9NUW8 1/20 0.64
CES1 P23141 1/20 0.63
ALDH1A1 P00352 3/20 0.63
HTT P42858 2/20 0.63
L3MBTL1 Q9Y468 1/20 0.62
KDM4E B2RXH2 1/20 0.60
GAA P10253 1/20 0.60
LMNA P02545 1/20 0.60
JAK2 O60674 1/20 0.57
JAK1 P23458 1/20 0.57
TYK2 P29597 1/20 0.57
PYGL P06737 1/20 0.56
KCNK3 O14649 1/20 0.56
KCNK9 Q9NPC2 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2009824 0.89 SMN1; SMN2 (0.70) MEN1KMT2AMAPTTP53NPC1
Hydrochloric Acid SCHEMBL2105080 0.87 MEN1 (0.64) MEN1KMT2AMAPTTP53NPC1
SCHEMBL2106312 0.86 CYP11B2 (0.61) MEN1KMT2AMAPTTP53NPC1
SCHEMBL2108038 0.86 KCNK3 (0.53) MEN1KMT2AMAPTTP53NPC1
SCHEMBL2005896 0.85 KCNK3 (0.76) MEN1KMT2AMAPTTP53NPC1
SCHEMBL7330825 0.84 JAK2 (0.66) MEN1KMT2AMAPTNPC1RAB9A
SCHEMBL2012930 0.82 KCNK3 (0.67) MEN1KMT2AMAPTNPC1RAB9A
SCHEMBL2107465 0.82 KCNK3 (0.74) MEN1KMT2ANPC1RAB9ACES1
SCHEMBL2227567 0.82 MEN1 (0.76) MEN1KMT2AMAPTTP53NPC1
SCHEMBL11573735 0.81 MEN1 (0.65) MEN1KMT2AMAPTTP53NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230373947-A1 AMIDE DERIVATIVES, PROCESS FOR PREPARATION THEREOF AND USE THEREOF AS INSECTICIDE MITSUI CHEMICALS, INC. (JP) 2023-11-23 US disclosed
US-11760742-B2 Amide derivatives, process for preparation thereof and use thereof as insecticide MITSUI CHEMICALS, INC. (JP) 2023-09-19 US disclosed
US-20210230135-A1 AMIDE DERIVATIVES, PROCESS FOR PREPARATION THEREOF AND USE THEREOF AS INSECTICIDE MITSUI CHEMICALS, INC. (JP) 2021-07-29 US disclosed
US-10995081-B2 Amide derivatives, process for preparation thereof and use thereof as insecticide MITSUI CHEMICALS, INC. (JP) 2021-05-04 US disclosed
US-10435385-B2 Amide derivatives, process for preparation thereof and use thereof as insecticide MITSUI CHEMICALS, INC. (JP) 2019-10-08 US disclosed
US-20180134681-A1 AMIDE DERIVATIVES, PROCESS FOR PREPARATION THEREOF AND USE THEREOF AS INSECTICIDE MITSUI CHEMICALS, INC. (JP) 2018-05-17 US disclosed
US-9920026-B2 Amide derivatives, process for preparation thereof and use thereof as insecticide MITSUI CHEMICALS, INC. (JP) 2018-03-20 US disclosed
EP-1714958-B9 AMIDE DERIVATIVES, PROCESS FOR PRODUCTION OF THE SAME, AND METHOD FOR APPLICATION THEREOF AS INSECTICIDE MITSUI CHEMICALS AGRO INC (JP) 2017-05-31 EP disclosed
EP-1714958-B1 AMIDE DERIVATIVES, PROCESS FOR PRODUCTION OF THE SAME, AND METHOD FOR APPLICATION THEREOF AS INSECTICIDE MITSUI CHEMICALS AGRO INC (JP) 2016-12-21 EP disclosed
US-20160002198-A1 AMIDE DERIVATIVES, PROCESS FOR PREPARATION THEREOF AND USE THEREOF AS INSECTICIDE MITSUI CHEMICALS, INC. (JP) 2016-01-07 US disclosed
US-7964735-B2 Insecticidal 3-acylaminobenzanilides BAYER CROPSCIENCE AG (DE) 2011-06-21 US disclosed
US-20090215623-A1 Insecticidal 3-acylaminobenzanilides BAYER CROPSCIENCE AG (DE) 2009-08-27 US disclosed
US-20090192167-A1 Insecticidal and fungicidal composition MITSUI CHEMICALS, INC. (JP) 2009-07-30 US disclosed
US-20090162453-A1 COMPOSITION FOR PREVENTING HARMFUL ORGANISMS MITSUI CHEMICALS, INC (JP) 2009-06-25 US disclosed
EP-1938685-A1 INSECTICIDAL AND BACTERICIDAL COMPOSITION Mitsui Chemicals, Inc. (JP) 2008-07-02 EP disclosed
EP-1913815-A1 PEST CONTROL COMPOSITION Mitsui Chemicals, Inc. (JP) 2008-04-23 EP disclosed
EP-1912933-A1 INSECTICIDAL 3-ACYLAMINOBENZANILIDES Bayer CropScience AG (DE) 2008-04-23 EP disclosed
US-20070275980-A1 Amide Derivatives, Process For Preparation Thereof And Use Thereof As Insecticide MITSUI CHEMICALS, INC. (JP) 2007-11-29 US disclosed
WO-2007017075-A1 INSECTICIDAL 3-ACYLAMINOBENZANILIDES BAYER CROPSCIENCE AG (DE) 2007-02-15 WO disclosed
EP-1714958-A1 AMIDE DERIVATIVES, PROCESS FOR PRODUCTION OF THE SAME, AND METHOD FOR APPLICATION THEREOF AS INSECTICIDE Mitsui Chemicals, Inc. (JP) 2006-10-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070275980-A1 Amide Derivatives, Process For Preparation Thereof And Use Thereof As Insecticide CYP1A1, CYP4B1, CYP2E1 MEN1 3376/4885KMT2A 1782/4885MAPT 4670/4885
US-20180134681-A1 AMIDE DERIVATIVES, PROCESS FOR PREPARATION THEREOF AND USE THEREOF AS INSECTICIDE CYP1A1, CYP4B1, CYP2E1 MEN1 3376/4885KMT2A 1782/4885MAPT 4670/4885
US-20160002198-A1 AMIDE DERIVATIVES, PROCESS FOR PREPARATION THEREOF AND USE THEREOF AS INSECTICIDE CYP1A1, CYP4B1, CYP2E1 MEN1 3376/4885KMT2A 1782/4885MAPT 4670/4885
US-20090192167-A1 Insecticidal and fungicidal composition NOX3, PRDX1, CYP4X1 MEN1 1780/4885KMT2A 2083/4885MAPT 4425/4885
US-20230373947-A1 AMIDE DERIVATIVES, PROCESS FOR PREPARATION THEREOF AND USE THEREOF AS INSECTICIDE DDT, CYP4B1, CYP2E1 MEN1 2759/4885KMT2A 565/4885MAPT 3134/4885
US-20210230135-A1 AMIDE DERIVATIVES, PROCESS FOR PREPARATION THEREOF AND USE THEREOF AS INSECTICIDE DDT, CYP4B1, CYP2E1 MEN1 2759/4885KMT2A 565/4885MAPT 3134/4885
US-20090215623-A1 Insecticidal 3-acylaminobenzanilides CBR3, AADAC, DDT MEN1 4278/4885KMT2A 1245/4885MAPT 4817/4885
US-10435385-B2 Amide derivatives, process for preparation thereof and use thereof as insecticide DDT, CYP4B1, CYP2E1 MEN1 2759/4885KMT2A 565/4885MAPT 3134/4885
US-20090162453-A1 COMPOSITION FOR PREVENTING HARMFUL ORGANISMS PRDX3, CYP1A1, GSTA1 MEN1 485/4885KMT2A 1594/4885MAPT 4443/4885
US-11760742-B2 Amide derivatives, process for preparation thereof and use thereof as insecticide DDT, CYP4B1, CYP2E1 MEN1 2759/4885KMT2A 565/4885MAPT 3134/4885
US-10995081-B2 Amide derivatives, process for preparation thereof and use thereof as insecticide DDT, CYP4B1, CYP2E1 MEN1 2759/4885KMT2A 565/4885MAPT 3134/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.