Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1075475 | 0.79 | FDPS (0.37) | LMNAFDPSTHRBDAOTSHR | |
| SCHEMBL19222041 | 0.77 | LMNA (0.36) | LMNAFDPSTHRBDAOTSHR | |
| SCHEMBL20099962 | 0.74 | TSHR (0.41) | LMNAFDPSTHRBDAOTSHR | |
| SCHEMBL278529 | 0.72 | L3MBTL1 (0.48) | LMNAFDPSTHRBDAOTSHR | |
| SCHEMBL21996528 | 0.71 | TSHR (0.44) | LMNAFDPSTHRBDAOTSHR | |
| SCHEMBL31581978 | 0.71 | TSHR (0.44) | LMNAFDPSTHRBDAOTSHR | |
| SCHEMBL20099857 | 0.70 | TSHR (0.38) | LMNAFDPSTHRBDAOTSHR | |
| SCHEMBL12181347 | 0.69 | — | — | |
| SCHEMBL10192257 | 0.69 | FDPS (0.38) | LMNAFDPSTHRBDAOTSHR | |
| SCHEMBL3320765 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3315492-A1 | PYRAZOLE DERIVATIVE, OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | Kissei Pharmaceutical Co., Ltd. (JP) | 2018-05-02 | — | — | EP | disclosed |