Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | CSF1R | P07333 | 1/20 | 0.44 |
| ▸ | RET | P07949 | 1/20 | 0.44 |
| ▸ | MET | P08581 | 1/20 | 0.44 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2038636 | 0.85 | ALDH1A1 (0.49) | ALDH1A1GAAKDM4EKMT2AMEN1 | |
| SCHEMBL19135994 | 0.83 | ALDH1A1 (0.49) | ALDH1A1GAAKDM4EHPGDPTGS1 | |
| SCHEMBL29756297 | 0.80 | ALDH1A1 (0.44) | ALDH1A1GAAKDM4EKMT2AMEN1 | |
| SCHEMBL286358 | 0.80 | ALDH1A1 (0.71) | ALDH1A1GAAKDM4EKMT2AMEN1 | |
| SCHEMBL17810146 | 0.78 | ALDH1A1 (0.39) | ALDH1A1GAAKDM4EKMT2AMEN1 | |
| SCHEMBL20100081 | 0.77 | ALDH1A1 (0.68) | ALDH1A1GAAKDM4EKMT2AMEN1 | |
| SCHEMBL8352177 | 0.77 | ALDH1A1 (0.68) | ALDH1A1GAAKDM4EKMT2AMEN1 | |
| SCHEMBL2036111 | 0.76 | TRPM8 (0.49) | ALDH1A1GAAKDM4EKMT2AHPGD | |
| SCHEMBL15924279 | 0.76 | ALDH1A1 (0.70) | ALDH1A1GAAKDM4EKMT2AMEN1 | |
| SCHEMBL872190 | 0.74 | PTGS1 (0.68) | ALDH1A1GAAKDM4EHPGDPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180116222-A1 | FUSED BICYCLIC HETEROCYCLE DERIVATIVES AS PESTICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180116222-A1 | FUSED BICYCLIC HETEROCYCLE DERIVATIVES AS PESTICIDES | DDT, CBR3, CYCS | ALDH1A1 987/4885GAA 3534/4885KDM4E 1838/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.