Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.61 |
| ▸ | DRD3 | P35462 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | ESR1 | P03372 | 3/20 | 0.56 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.56 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.56 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.56 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.56 |
| ▸ | STS | P08842 | 5/20 | 0.56 |
| ▸ | CNR2 | P34972 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6932101 | 1.00 | HRH3 (0.61) | HRH3DRD3ALDH1A1TSHRLMNA | |
| SCHEMBL20100236 | 1.00 | HRH3 (0.61) | HRH3DRD3ALDH1A1TSHRLMNA | |
| SCHEMBL3157861 | 1.00 | HRH3 (0.61) | HRH3DRD3ALDH1A1TSHRLMNA | |
| SCHEMBL16606224 | 1.00 | HRH3 (0.61) | HRH3DRD3ALDH1A1TSHRLMNA | |
| SCHEMBL11527051 | 0.94 | HRH3 (0.64) | HRH3DRD3TSHRLMNATP53 | |
| SCHEMBL9458309 | 0.94 | ALDH1A1 (0.67) | ALDH1A1TSHRLMNANPC1MAPT | |
| SCHEMBL16632600 | 0.94 | ALDH1A1 (0.67) | ALDH1A1TSHRLMNANPC1MAPT | |
| SCHEMBL4853372 | 0.94 | ALDH1A1 (0.67) | ALDH1A1TSHRLMNANPC1MAPT | |
| SCHEMBL9458671 | 0.94 | ALDH1A1 (0.67) | ALDH1A1TSHRLMNANPC1MAPT | |
| SCHEMBL9458337 | 0.94 | ALDH1A1 (0.67) | ALDH1A1TSHRLMNANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180118917-A1 | NAPHTHOIC ACID ESTER PLASTICIZERS AND METHOD OF MAKING | EXXONMOBIL RESEARCH AND ENGINEERING COMPAY | 2018-05-03 | — | — | US | disclosed |
| US-20180118917-A1 | NAPHTHOIC ACID ESTER PLASTICIZERS AND METHOD OF MAKING | EXXONMOBIL RESEARCH AND ENGINEERING COMPAY | 2018-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180118917-A1 | NAPHTHOIC ACID ESTER PLASTICIZERS AND METHOD OF MAKING | FASN, ADH1A, ALOX15 | HRH3 3463/4885DRD3 1328/4885ALDH1A1 172/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.