SCHEMBL20100324

SCHEMBL20100324

C=C(C(=O)NC(=O)C1CCC(C(F)(F)F)CC1)C(F)(F)F

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TGM2 P21980 1/20 0.32
PI4KB Q9UBF8 1/20 0.31
ALDH1A1 P00352 1/20 0.30
POLB P06746 1/20 0.30
HPGD P15428 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20100334 0.83 PI4KB (0.33) PI4KBALDH1A1POLBHPGDKMT2A
SCHEMBL20100343 0.75 KMT2A (0.31) KMT2A
SCHEMBL28039756 0.71 CHRNB2 (0.38) PI4KBALDH1A1POLBKMT2A
SCHEMBL21061620 0.71 PI4KB (0.37) PI4KBPOLBKMT2A
SCHEMBL20100423 0.68 GLA (0.34) PI4KBALDH1A1POLB
SCHEMBL20100337 0.67 KMT2A (0.32) KMT2A
SCHEMBL28649535 0.67 CHRNB2 (0.38) PI4KB
SCHEMBL4753774 0.66 SMN1; SMN2 (0.38) PI4KBPOLBKMT2A
SCHEMBL4753772 0.66 SMN1; SMN2 (0.38) PI4KBPOLBKMT2A
SCHEMBL671388 0.65 LMNA (0.43) KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10042259-B2 Topcoat compositions and pattern-forming methods ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2018-08-07 US disclosed
US-10042259-B2 Topcoat compositions and pattern-forming methods ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2018-08-07 US disclosed
US-20180118970-A1 TOPCOAT COMPOSITIONS AND PATTERN-FORMING METHODS ROHM AND HAAS ELECTRONIC MATERIALS LLC 2018-05-03 US disclosed
US-20180118970-A1 TOPCOAT COMPOSITIONS AND PATTERN-FORMING METHODS ROHM AND HAAS ELECTRONIC MATERIALS LLC 2018-05-03 US disclosed