SCHEMBL20100327

SCHEMBL20100327

C=C(C)C(=O)OCC(=O)N(C(=O)C(C)(C)C)C1CC(F)C(F)C(F)C1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
THRB P10828 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20100397 0.70 ALDH1A1 (0.33) ALDH1A1THRB
SCHEMBL27360000 0.63 THRB (0.48) ALDH1A1THRB
SCHEMBL17589180 0.63 TSHR (0.47) ALDH1A1THRB
SCHEMBL20100293 0.61 TSHR (0.42) ALDH1A1THRB
SCHEMBL27850609 0.59 THRB (0.48) ALDH1A1THRB
SCHEMBL28641912 0.59 TSHR (0.50) ALDH1A1THRB
SCHEMBL2421204 0.59 TSHR (0.50) ALDH1A1THRB
SCHEMBL865704 0.59 TSHR (0.50) ALDH1A1THRB
Adamantane SCHEMBL29167166 0.58 THRB (0.52) ALDH1A1THRB
SCHEMBL587102 0.58 TSHR (0.54) ALDH1A1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10042259-B2 Topcoat compositions and pattern-forming methods ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2018-08-07 US disclosed
US-10042259-B2 Topcoat compositions and pattern-forming methods ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2018-08-07 US disclosed
US-20180118970-A1 TOPCOAT COMPOSITIONS AND PATTERN-FORMING METHODS ROHM AND HAAS ELECTRONIC MATERIALS LLC 2018-05-03 US disclosed
US-20180118970-A1 TOPCOAT COMPOSITIONS AND PATTERN-FORMING METHODS ROHM AND HAAS ELECTRONIC MATERIALS LLC 2018-05-03 US disclosed