SCHEMBL865704

SCHEMBL865704

C=C(C)C(=O)OCC(=O)Cl

nearest known ligand 0.50

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.50
THRB P10828 1/20 0.47
ALDH1A1 P00352 3/20 0.44
TDP1 Q9NUW8 2/20 0.34
POLB P06746 1/20 0.34
APEX1 P27695 1/20 0.34
HTT P42858 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2421204 0.86 TSHR (0.50) TSHRTHRBALDH1A1TDP1POLB
SCHEMBL12213191 0.81 TSHR (0.35) TSHRTHRBALDH1A1TDP1
SCHEMBL27713534 0.80 TSHR (0.45) TSHRTHRBALDH1A1TDP1POLB
SCHEMBL587102 0.80 TSHR (0.54) TSHRTHRBALDH1A1TDP1POLB
SCHEMBL21313125 0.80 TSHR (0.54) TSHRTHRBALDH1A1TDP1POLB
SCHEMBL9704499 0.80 TSHR (0.54) TSHRTHRBALDH1A1TDP1POLB
SCHEMBL12687399 0.80
SCHEMBL5098395 0.80 TSHR (0.54) TSHRTHRBALDH1A1TDP1POLB
SCHEMBL1389549 0.80 TSHR (0.54) TSHRTHRBALDH1A1TDP1POLB
SCHEMBL29032038 0.79 TSHR (0.32) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 164 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11281102-B2 Fluorine-containing monomer, fluorine-containing polymer, pattern forming composition using same, and pattern forming method of same CENTRAL GLASS COMPANY, LIMITED (JP) 2022-03-22 US disclosed
US-11111320-B2 Addition-fragmentation oligomers 3M INNOVATIVE PROPERTIES COMPANY (US) 2021-09-07 US disclosed
EP-3685199-B1 METHODS OF MANUFACTURING COATED CONTACT LENSES COOPERVISION INT LTD (GB) 2021-08-04 EP disclosed
US-11067831-B2 Methods of manufacturing coated contact lenses COOPERVISION INTERNATIONAL LIMITED (GB) 2021-07-20 US disclosed
EP-3326711-B1 GRAFT COPOLYMER FUNCTIONALIZED ARTICLE 3M INNOVATIVE PROPERTIES CO (US) 2021-07-07 EP disclosed
CN-110730790-B Fluorine-containing monomer, fluorine-containing polymer, composition for forming pattern using same, and method for forming pattern using same 中央硝子株式会社 2021-06-15 CN disclosed
CN-105717744-B Monomer, polymer, resist composition and patterning method 信越化学工业株式会社 2020-10-23 CN disclosed
EP-3685199-A1 METHODS OF MANUFACTURING COATED CONTACT LENSES CooperVision International Holding Company, LP (BB) 2020-07-29 EP disclosed
EP-2675783-B1 ADDITION-FRAGMENTATION AGENTS 3M INNOVATIVE PROPERTIES CO (US) 2020-04-22 EP disclosed
US-20200089116-A1 Fluorine-Containing Monomer, Fluorine-Containing Polymer, Pattern Forming Composition Using Same, and Pattern Forming Method of Same CENTRAL GLASS COMPANY, LIMITED (JP) 2020-03-19 US disclosed
US-20110177453-A1 Fluorine-Containing Sulfonates Having Polymerizable Anions and Manufacturing Method Therefor, Fluorine-Containing Resins, Resist Compositions, and Pattern-Forming Method Using Same CENTRAL GLASS COMPANY, LIMITED (JP) 2011-07-21 US disclosed
US-20110177453-A1 Fluorine-Containing Sulfonates Having Polymerizable Anions and Manufacturing Method Therefor, Fluorine-Containing Resins, Resist Compositions, and Pattern-Forming Method Using Same CENTRAL GLASS COMPANY, LIMITED (JP) 2011-07-21 US disclosed
US-20110151381-A1 FLUORINATED MONOMER, FLUORINATED POLYMER, RESIST COMPOSITION, AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2011-06-23 US disclosed
US-20110151381-A1 FLUORINATED MONOMER, FLUORINATED POLYMER, RESIST COMPOSITION, AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2011-06-23 US disclosed
US-20110151381-A1 FLUORINATED MONOMER, FLUORINATED POLYMER, RESIST COMPOSITION, AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2011-06-23 US disclosed
CN-101809064-A Polyamide resin, photosensitive resin composition, method for forming cured relief pattern, and semiconductor device ASAHI KASEI E MATERIALS CORP 2010-08-18 CN disclosed
WO-2010044372-A1 FLUORINE-CONTAINING SULFONATES HAVING POLYMERIZABLE ANIONS AND MANUFACTURING METHOD THEREFOR, FLUORINE-CONTAINING RESINS, RESIST COMPOSITIONS, AND PATTERN-FORMING METHOD USING SAME セントラル硝子株式会社 (JP) 2010-04-22 WO disclosed
US-4855282-A Recording material and method for producing the same FUJI PHOTO FILM CO., LTD. (JP) 1989-08-08 US disclosed
US-4378411-A HAVING ETHLENICALLY UNSATURATED PEPTIDE GROUPS; FOR GRAPHIC ARTS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1983-03-29 US disclosed
US-4304705-A Radiation-curable polymers containing pendant unsaturated peptide groups derived from azlactone polymers MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1981-12-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110151381-A1 FLUORINATED MONOMER, FLUORINATED POLYMER, RESIST COMPOSITION, AND PATTERNING PROCESS AFF1, H1-0, FRG1 TSHR 2728/4885THRB 2552/4885ALDH1A1 629/4885
US-20110177453-A1 Fluorine-Containing Sulfonates Having Polymerizable Anions and Manufacturing Method Therefor, Fluorine-Containing Resins, Resist Compositions, and Pattern-Forming Method Using Same WASF2, EEF2, IKZF2 TSHR 2715/4885THRB 3531/4885ALDH1A1 2304/4885
US-11111320-B2 Addition-fragmentation oligomers ECPAS, ITGA8, NBAS TSHR 4794/4885THRB 4239/4885ALDH1A1 2212/4885
US-11281102-B2 Fluorine-containing monomer, fluorine-containing polymer, pattern forming composition using same, and pattern forming method of same AFF4, AFF1, AFF2 TSHR 1939/4885THRB 4083/4885ALDH1A1 1410/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.