Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20100317 | 0.84 | TSHR (0.39) | TSHRALDH1A1THRBALOX15 | |
| SCHEMBL20100364 | 0.81 | TP53 (0.33) | TSHRALOX15CYP1A2PKMPTK2B | |
| SCHEMBL17589180 | 0.75 | TSHR (0.47) | TSHRALDH1A1THRBATM | |
| SCHEMBL9704499 | 0.74 | TSHR (0.54) | TSHRALDH1A1THRBGAAMAPT | |
| SCHEMBL20100360 | 0.72 | TDP1 (0.56) | ALDH1A1ALOX15MEN1MAPTKMT2A | |
| SCHEMBL18656239 | 0.72 | THRB (0.46) | TSHRALDH1A1THRBPKM | |
| SCHEMBL15807755 | 0.71 | THRB (0.46) | TSHRALDH1A1THRBMEN1MAPT | |
| SCHEMBL396824 | 0.70 | TSHR (0.50) | TSHRALDH1A1THRBKMT2A | |
| SCHEMBL5098395 | 0.69 | TSHR (0.54) | TSHRALDH1A1THRBGAAMAPT | |
| SCHEMBL21313125 | 0.69 | TSHR (0.54) | TSHRALDH1A1THRBGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10042259-B2 | Topcoat compositions and pattern-forming methods | ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) | 2018-08-07 | — | — | US | disclosed |
| US-10042259-B2 | Topcoat compositions and pattern-forming methods | ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) | 2018-08-07 | — | — | US | disclosed |
| US-20180118970-A1 | TOPCOAT COMPOSITIONS AND PATTERN-FORMING METHODS | ROHM AND HAAS ELECTRONIC MATERIALS LLC | 2018-05-03 | — | — | US | disclosed |
| US-20180118970-A1 | TOPCOAT COMPOSITIONS AND PATTERN-FORMING METHODS | ROHM AND HAAS ELECTRONIC MATERIALS LLC | 2018-05-03 | — | — | US | disclosed |