SCHEMBL20100405

SCHEMBL20100405

C=C(C)C(=O)NC(C(=O)N(C)C(=O)C(F)(F)F)C(F)(F)F

nearest known ligand 0.37

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TGFBR1 P36897 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20100373 0.81 TGFBR1 (0.37) TGFBR1
SCHEMBL20100378 0.80 TGFBR1 (0.36) TGFBR1
SCHEMBL20457124 0.69 ALDH1A1 (0.31)
SCHEMBL29342172 0.69 TGFBR1 (0.41) TGFBR1
SCHEMBL9004789 0.69 CHRM2 (0.38)
SCHEMBL21342532 0.65 TGFBR1 (0.50) TGFBR1
SCHEMBL20100352 0.65 TSHR (0.32)
SCHEMBL1820299 0.62 TGFBR1 (0.50) TGFBR1
SCHEMBL472271 0.62 TGFBR1 (0.55) TGFBR1
SCHEMBL8734663 0.61 TGFBR1 (0.41) TGFBR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180118970-A1 TOPCOAT COMPOSITIONS AND PATTERN-FORMING METHODS ROHM AND HAAS ELECTRONIC MATERIALS LLC 2018-05-03 US disclosed
US-20180118970-A1 TOPCOAT COMPOSITIONS AND PATTERN-FORMING METHODS ROHM AND HAAS ELECTRONIC MATERIALS LLC 2018-05-03 US disclosed