Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 9/20 | 0.67 |
| ▸ | PGR | P06401 | 7/20 | 0.67 |
| ▸ | CASR | P41180 | 3/20 | 0.42 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2006930 | 0.79 | NR3C1 (0.78) | NR3C1PGRCASRSMN1; SMN2 | |
| SCHEMBL2002566 | 0.79 | NR3C1 (0.59) | NR3C1PGRCASRMMEL1CA1 | |
| SCHEMBL2005613 | 0.78 | NR3C1 (0.62) | NR3C1PGRCASRHTT | |
| SCHEMBL2005610 | 0.78 | NR3C1 (0.62) | NR3C1PGRCASRHTT | |
| SCHEMBL2004253 | 0.75 | NR3C1 (0.69) | NR3C1PGRCASR | |
| SCHEMBL2008107 | 0.75 | NR3C1 (1.00) | NR3C1PGRCASRCNR1 | |
| SCHEMBL2002847 | 0.69 | NR3C1 (0.45) | NR3C1PGRCASRCNR1 | |
| SCHEMBL2004275 | 0.69 | NR3C1 (0.51) | NR3C1PGRCNR1HTT | |
| SCHEMBL2009504 | 0.68 | CASR (0.49) | NR3C1PGRCASRMMEL1 | |
| SCHEMBL2009918 | 0.68 | CASR (0.49) | NR3C1PGRCASRMMEL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7960365-B2 | Compounds with medicinal effects due to interaction with the glucocorticoid receptor | N.V. ORGANON (NL) | 2011-06-14 | — | — | US | disclosed |