Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 10/20 | 0.69 |
| ▸ | PGR | P06401 | 8/20 | 0.69 |
| ▸ | CASR | P41180 | 3/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.40 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.40 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.40 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.40 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.40 |
| ▸ | ACLY | P53396 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | FPR2 | P25090 | 1/20 | 0.39 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.39 |
| ▸ | NMT1 | P30419 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2006930 | 0.83 | NR3C1 (0.78) | NR3C1PGRCASR | |
| SCHEMBL2008128 | 0.81 | NR3C1 (0.54) | NR3C1PGRACLYNMT1 | |
| SCHEMBL2008107 | 0.77 | NR3C1 (1.00) | NR3C1PGRCASR | |
| SCHEMBL2005610 | 0.76 | NR3C1 (0.62) | NR3C1PGRCASR | |
| SCHEMBL2005613 | 0.76 | NR3C1 (0.62) | NR3C1PGRCASR | |
| SCHEMBL2010050 | 0.75 | NR3C1 (0.67) | NR3C1PGRCASR | |
| SCHEMBL2002566 | 0.73 | NR3C1 (0.59) | NR3C1PGRCASRPSEN1PSEN2 | |
| SCHEMBL2006413 | 0.71 | ACLY (0.44) | NR3C1PGRACLYFPR2PROKR1 | |
| SCHEMBL2004967 | 0.71 | NR3C1 (0.76) | NR3C1PGRTP53 | |
| SCHEMBL2011430 | 0.69 | NR3C1 (0.78) | NR3C1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7960365-B2 | Compounds with medicinal effects due to interaction with the glucocorticoid receptor | N.V. ORGANON (NL) | 2011-06-14 | — | — | US | disclosed |