Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | GAA | P10253 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 2/20 | 0.44 |
| ▸ | MMP3 | P08254 | 2/20 | 0.44 |
| ▸ | MMP7 | P09237 | 2/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6813845 | 0.79 | ALDH1A1 (0.60) | KDM4EGAAALDH1A1KMT2ATSHR | |
| SCHEMBL12631368 | 0.78 | LMNA (0.65) | ALDH1A1MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL2019135 | 0.73 | HPGD (0.53) | GAAALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL10724386 | 0.72 | ALDH1A1 (1.00) | KDM4EGAAALDH1A1MEN1KMT2A | |
| SCHEMBL13217943 | 0.71 | ALDH1A1 (0.58) | GAAALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL31388283 | 0.70 | ALDH1A1 (0.84) | KDM4EGAAALDH1A1MEN1KMT2A | |
| SCHEMBL8745861 | 0.68 | MCOLN3 (0.54) | KDM4EALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL7050097 | 0.67 | PSEN1 (0.54) | KDM4EGAAALDH1A1KMT2ATSHR | |
| SCHEMBL10445162 | 0.67 | ALDH1A1 (0.85) | KDM4EGAAALDH1A1MEN1KMT2A | |
| SCHEMBL1902263 | 0.67 | ALDH1A1 (0.85) | KDM4EGAAALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011073277-A1 | PIPERIDINE ARYL SULFONAMIDE DERIVATIVES AS Kv1.3 MODULATORS | EVOTEC AG (DE) | 2011-06-23 | — | — | WO | claimed |