Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.47 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.47 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.47 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.47 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.47 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13217943 | 0.91 | ALDH1A1 (0.58) | ALDH1A1TSHRGAAKMT2AMAPT | |
| SCHEMBL17661784 | 0.84 | ALDH1A1 (0.54) | ALDH1A1KDM4EL3MBTL1KMT2ARAB9A | |
| SCHEMBL5915269 | 0.84 | PSEN1 (0.60) | ALDH1A1L3MBTL1KMT2AMAPTLMNA | |
| SCHEMBL16221279 | 0.84 | ALDH1A1 (0.54) | ALDH1A1KDM4EL3MBTL1KMT2ARAB9A | |
| SCHEMBL17651673 | 0.84 | ALDH1A1 (0.54) | ALDH1A1KDM4EL3MBTL1KMT2ARAB9A | |
| SCHEMBL13218033 | 0.80 | PSEN1 (0.56) | ALDH1A1L3MBTL1KMT2AMAPTLMNA | |
| SCHEMBL2010052 | 0.79 | KDM4E (0.59) | ALDH1A1TSHRKDM4EGAAKMT2A | |
| SCHEMBL13217834 | 0.78 | ALDH1A1 (0.60) | ALDH1A1KDM4EL3MBTL1KMT2ARAB9A | |
| SCHEMBL5251498 | 0.78 | PSEN1 (0.64) | ALDH1A1KMT2AMAPTLMNAPSEN1 | |
| SCHEMBL2019135 | 0.75 | HPGD (0.53) | ALDH1A1GAAKMT2AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040132809-A1 | Cell adhesion inhibitors | BIOGEN, INC. | 2004-07-08 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040132809-A1 | Cell adhesion inhibitors | VCAM1, ICAM1, EPCAM | ALDH1A1 631/4885TSHR 1354/4885KDM4E 2712/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.