Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | ENPP3 | O14638 | 3/20 | 0.49 |
| ▸ | ENPP1 | P22413 | 3/20 | 0.49 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | ELOVL6 | Q9H5J4 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2012885 | 0.83 | ALDH1A1 (0.55) | HPGDMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL12631368 | 0.81 | LMNA (0.65) | HPGDMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL2013828 | 0.80 | ALDH1A1 (0.57) | HPGDMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL12629075 | 0.80 | ALDH1A1 (0.57) | HPGDMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL6813845 | 0.75 | ALDH1A1 (0.60) | KMT2AALDH1A1LMNAGAAMAPT | |
| SCHEMBL2015023 | 0.75 | DPP4 (0.48) | MEN1KMT2AALDH1A1TDP1LMNA | |
| SCHEMBL12628296 | 0.75 | DPP4 (0.48) | MEN1KMT2AALDH1A1TDP1LMNA | |
| SCHEMBL2032885 | 0.74 | GAA (0.56) | MEN1KMT2AALDH1A1LMNAGAA | |
| SCHEMBL2709244 | 0.74 | BRD4 (0.71) | KMT2AALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL2010052 | 0.73 | KDM4E (0.59) | HPGDMEN1KMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011073269-A1 | PIPERIDINE ARYL SULFONAMIDE DERIVATIVES AS KV1.3 MODULATORS | EVOTEC AG (DE) | 2011-06-23 | — | — | WO | claimed |
| WO-2011073269-A1 | PIPERIDINE ARYL SULFONAMIDE DERIVATIVES AS KV1.3 MODULATORS | EVOTEC AG (DE) | 2011-06-23 | — | — | WO | disclosed |