Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HK1 | P19367 | 1/20 | 0.43 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17548514 | 0.78 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2HK1HKDC1LMNA | |
| SCHEMBL820350 | 0.75 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2HK1HKDC1LMNA | |
| SCHEMBL28988803 | 0.68 | CYP11B2 (0.73) | ALDH1A1SMN1; SMN2HK1HKDC1LMNA | |
| SCHEMBL28091859 | 0.65 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2HK1HKDC1LMNA | |
| SCHEMBL3604201 | 0.64 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2HK1HKDC1LMNA | |
| SCHEMBL28181079 | 0.64 | HSD17B10 (0.67) | ALDH1A1SMN1; SMN2HK1HKDC1LMNA | |
| SCHEMBL822744 | 0.63 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2HK1HKDC1LMNA | |
| SCHEMBL10067380 | 0.63 | CYP11B2 (0.68) | ALDH1A1SMN1; SMN2HK1HKDC1LMNA | |
| SCHEMBL1881428 | 0.62 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2HK1HKDC1LMNA | |
| SCHEMBL1881426 | 0.62 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2HK1HKDC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180118681-A1 | CANNABINOID TYPE 1 RECEPTOR MODULATORS | THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN (GB) | 2018-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180118681-A1 | CANNABINOID TYPE 1 RECEPTOR MODULATORS | CNR1, CNR2, GPR18 | ALDH1A1 1498/4885SMN1; SMN2 3732/4885HK1 2556/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.