Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | GPR3 | P46089 | 1/20 | 0.47 |
| ▸ | HK1 | P19367 | 1/20 | 0.44 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16376930 | 0.81 | ALDH1A1 (0.38) | ALDH1A1LMNAHSD17B10CYP2C19HPGD | |
| SCHEMBL13321059 | 0.76 | KDM4E (0.65) | ALDH1A1LMNAHSD17B10CYP2C19HPGD | |
| SCHEMBL10067380 | 0.76 | CYP11B2 (0.68) | ALDH1A1LMNAHSD17B10CYP2C19HPGD | |
| SCHEMBL822744 | 0.76 | ALDH1A1 (0.59) | ALDH1A1LMNAHSD17B10CYP2C19HPGD | |
| SCHEMBL13542540 | 0.76 | GPR3 (0.52) | ALDH1A1LMNAHSD17B10CYP2C19HPGD | |
| SCHEMBL20100535 | 0.75 | ALDH1A1 (0.43) | ALDH1A1LMNAHSD17B10CYP2C19HPGD | |
| SCHEMBL10529112 | 0.74 | ALDH1A1 (0.58) | ALDH1A1LMNAHSD17B10CYP2C19HPGD | |
| SCHEMBL4785226 | 0.74 | ALDH1A1 (0.57) | ALDH1A1LMNAHSD17B10CYP2C19HPGD | |
| SCHEMBL29078839 | 0.74 | ALDH1A1 (0.58) | ALDH1A1LMNAHSD17B10CYP2C19HPGD | |
| SCHEMBL28186733 | 0.74 | ALDH1A1 (0.57) | ALDH1A1LMNAHSD17B10CYP2C19HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110288116-A1 | IAP INHIBITORS | TETRALOGIC PHARMACEUITCAL CORPORATION (US) | 2011-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110288116-A1 | IAP INHIBITORS | XIAP, BIRC5, BIRC7 | ALDH1A1 4283/4885LMNA 994/4885HSD17B10 3760/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.