Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.66 |
| ▸ | DAO | P14920 | 1/20 | 0.61 |
| ▸ | CES2 | O00748 | 1/20 | 0.57 |
| ▸ | CES1 | P23141 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 4/20 | 0.56 |
| ▸ | HPGDS | O60760 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | DRD3 | P35462 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | GSK3B | P49841 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24573314 | 0.86 | DAO (0.64) | ALDH1A1KMT2ADAOCES2CES1 | |
| SCHEMBL6495865 | 0.85 | KMT2A (0.66) | ALDH1A1KMT2ADAOCES2CES1 | |
| SCHEMBL1244072 | 0.83 | CES2 (0.73) | ALDH1A1KMT2ADAOCES2CES1 | |
| SCHEMBL13437714 | 0.82 | CES2 (0.73) | ALDH1A1KMT2ADAOCES2CES1 | |
| SCHEMBL29171652 | 0.82 | CES2 (0.61) | ALDH1A1KMT2ADAOCES2CES1 | |
| SCHEMBL8308134 | 0.81 | DAO (0.57) | ALDH1A1KMT2ADAOCES2CES1 | |
| SCHEMBL21820 | 0.80 | HSD17B1 (0.63) | CLK1DYRK1ADYRK1B | |
| SCHEMBL9260830 | 0.79 | ALDH1A1 (1.00) | ALDH1A1KMT2ADAOCES2CES1 | |
| SCHEMBL8825107 | 0.79 | HPGD (0.59) | ALDH1A1KMT2ADAOHPGDHPGDS | |
| SCHEMBL17941543 | 0.78 | HPGD (0.58) | ALDH1A1KMT2AHPGDHPGDSCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107486158-A | There is the montmorillonite-base sorbing material its preparation method of solidification function to mercury in river bottom mud | 北京清水润土环保科技有限公司 | 2017-12-19 | — | — | CN | claimed |
| US-20170043196-A1 | Fire Extinguishing Composition Comprising Heterocyclic Compounds | XI'AN J&R FIRE FIGHTING EQUIPMENT CO., LTD. (CN) | 2017-02-16 | — | — | US | claimed |
| EP-3095485-A1 | FIRE EXTINGUISHING COMPOSITION COMPRISING HETEROCYCLIC COMPOUNDS | Xi'an J&R Fire Fighting Equipment Co., Ltd. (CN) | 2016-11-23 | — | — | EP | claimed |
| CN-108864326-B | Photocurable composition and use thereof | 湖北固润科技股份有限公司 | 2020-10-13 | — | — | CN | disclosed |
| CN-108864136-B | 3, 4-ethylenedioxythiophene derivative and preparation method and application thereof | 湖北固润科技股份有限公司 | 2020-04-24 | — | — | CN | disclosed |
| CN-108864326-A | Photocurable composition and its application | 湖北固润科技股份有限公司 | 2018-11-23 | — | — | CN | disclosed |
| CN-108864136-A | 3,4- ethylenedioxy thiophene derivative and its preparation method and application | 湖北固润科技股份有限公司 | 2018-11-23 | — | — | CN | disclosed |
| CN-107486158-A | There is the montmorillonite-base sorbing material its preparation method of solidification function to mercury in river bottom mud | 北京清水润土环保科技有限公司 | 2017-12-19 | — | — | CN | disclosed |
| US-20170043196-A1 | Fire Extinguishing Composition Comprising Heterocyclic Compounds | XI'AN J&R FIRE FIGHTING EQUIPMENT CO., LTD. (CN) | 2017-02-16 | — | — | US | disclosed |
| EP-3095485-A1 | FIRE EXTINGUISHING COMPOSITION COMPRISING HETEROCYCLIC COMPOUNDS | Xi'an J&R Fire Fighting Equipment Co., Ltd. (CN) | 2016-11-23 | — | — | EP | disclosed |
| CN-102432591-B | Novel synthesis process of nonsteroidal antiinflammatory agent, namely, 5-benzoyl-alpha-methyl-2-thiopheneacetic acid | SOUTHEAST PHARMACEUTICALS INC | 2013-12-11 | — | — | CN | disclosed |
| WO-2007050049-A1 | CARBONYL-FUNCTIONALIZED THIOPHENE COMPOUNDS AND RELATED DEVICE STRUCTURES | NORTHWESTERN UNIVERSITY (US) | 2007-05-03 | — | — | WO | disclosed |
| US-20060186401-A1 | Carbonyl-functionalized thiophene compounds and related device structures | POLYERA CORPORATION | 2006-08-24 | — | — | US | disclosed |
| EP-0748802-B1 | Process for the preparation of alpha-methyl-2-thiopheneacetic acid derivatives | ERREGIERRE SPA (IT) | 2001-03-28 | — | — | EP | disclosed |
| US-5650522-A | MULTISTAGE PROCESS TO FORM KETONE, THEN REACTION WITH HALODIESTER COMPOUND TO FORM KETOTHIOPHENEDIESTER THEN SAPONIFICATION WITH ALKALI AND MINERAL ACID | ERREGIERRE S.P.A. (IT) | 1997-07-22 | — | — | US | disclosed |
| EP-0748802-A1 | Process for the preparation of alpha-methyl-2-thiopheneacetic acid derivatives | ERREGIERRE S.p.A. (IT) | 1996-12-18 | — | — | EP | disclosed |
| EP-0339599-B1 | Process for producing acylaromatic compounds | SUMITOMO CHEMICAL CO (JP) | 1996-08-21 | — | — | EP | disclosed |
| US-5235068-A | Using a boron trifluoride complex catalyst to react an aromatic compound and anhydride or acid | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-08-10 | — | — | US | disclosed |
| EP-0339599-A2 | Process for producing acylaromatic compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1989-11-02 | — | — | EP | disclosed |
| US-4282246-A | Antidiabetic furancarboxylic and thiphenecarboxylic acids | PFIZER INC. (US) | 1981-08-04 | — | — | US | disclosed |