SCHEMBL20101409

SCHEMBL20101409

COP(=O)(OC)OCCCCCNC(=O)Cc1cnc2ccccc2c1-c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TACR1 P25103 1/20 0.39
HPGD P15428 2/20 0.39
ALDH1A1 P00352 2/20 0.39
HTT P42858 2/20 0.39
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
TERT O14746 3/20 0.39
LTB4R Q15722 1/20 0.39
TP53 P04637 1/20 0.38
TACR3 P29371 1/20 0.38
MAPT P10636 2/20 0.38
HCRTR1 O43613 1/20 0.38
GAA P10253 1/20 0.38
KMT2A Q03164 1/20 0.38
LMNA P02545 1/20 0.38
POLB P06746 1/20 0.38
DHODH Q02127 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20101355 0.88 MTNR1A (0.44) HPGDALDH1A1MAPTKMT2ALMNA
SCHEMBL17955300 0.85 TERT (0.42) TACR1HTTTERTLTB4RTP53
SCHEMBL17955270 0.84 TERT (0.41) TACR1HPGDALDH1A1HTTCYP1A2
SCHEMBL20375671 0.84 MTNR1A (0.36) HPGDALDH1A1TERTLMNAPOLB
SCHEMBL16627089 0.82 MTNR1A (0.45) TACR1HPGDALDH1A1HTTCYP1A2
SCHEMBL23365643 0.81 KMT2A (0.41) TACR1HPGDALDH1A1HTTCYP1A2
SCHEMBL17955297 0.81 KMT2A (0.39) TACR1HPGDALDH1A1HTTTERT
SCHEMBL17955295 0.81 KMT2A (0.39) TACR1HPGDALDH1A1HTTCYP1A2
SCHEMBL16627109 0.81 CYP1A2 (0.47) TACR1HPGDALDH1A1HTTCYP1A2
SCHEMBL20101278 0.80 KMT2A (0.41) TACR1HPGDALDH1A1HTTCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3052107-B1 ORGANIC COMPOUNDS TO TREAT HEPATITIS B VIRUS NOVARTIS AG (CH) 2018-05-02 EP disclosed