Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 9/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 8/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20101409 | 0.88 | TACR1 (0.39) | KDM4EALDH1A1MAPTKMT2ALMNA | |
| SCHEMBL17955289 | 0.88 | MTNR1A (0.42) | MTNR1AMTNR1BKDM4EALDH1A1MAPT | |
| SCHEMBL17955301 | 0.87 | MTNR1A (0.41) | MTNR1AMTNR1BMAPTHDAC1HDAC6 | |
| SCHEMBL17954339 | 0.86 | MTNR1A (0.49) | MTNR1AMTNR1BKDM4EALDH1A1MAPT | |
| SCHEMBL17955298 | 0.85 | MTNR1A (0.42) | MTNR1AMTNR1BKDM4EALDH1A1MAPT | |
| SCHEMBL20375671 | 0.79 | MTNR1A (0.36) | MTNR1AMTNR1BKDM4EALDH1A1LMNA | |
| SCHEMBL16624688 | 0.78 | ALDH1A1 (0.50) | MTNR1AMTNR1BKDM4EALDH1A1MAPT | |
| SCHEMBL17954338 | 0.77 | ALDH1A1 (0.49) | MTNR1AMTNR1BKDM4EALDH1A1MAPT | |
| SCHEMBL17955270 | 0.76 | TERT (0.41) | ALDH1A1MEN1KMT2ALMNAHPGD | |
| SCHEMBL17955300 | 0.75 | TERT (0.42) | MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052107-B1 | ORGANIC COMPOUNDS TO TREAT HEPATITIS B VIRUS | NOVARTIS AG (CH) | 2018-05-02 | — | — | EP | disclosed |